SCHEMBL1369788

SCHEMBL1369788

Nc1ccc2c(c1)S(=O)(=O)c1ccccc1-2

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.64
L3MBTL1 Q9Y468 2/20 0.53
NPSR1 Q6W5P4 2/20 0.53
KDM4E B2RXH2 1/20 0.53
GAA P10253 1/20 0.53
MAPT P10636 1/20 0.53
CASP1 P29466 1/20 0.53
RECQL P46063 1/20 0.53
CASP7 P55210 1/20 0.53
HSD17B10 Q99714 1/20 0.53
PTPRC P08575 2/20 0.52
CHEK1 O14757 2/20 0.51
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
NPC1 O15118 2/20 0.48
ALDH1A1 P00352 2/20 0.48
RAB9A P51151 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
TP53 P04637 1/20 0.48
CYP3A4 P08684 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11550711 0.98 GPR3 (0.61) GPR3L3MBTL1NPSR1KDM4EGAA
SCHEMBL14174131 0.96 GPR3 (0.59) GPR3L3MBTL1NPSR1KDM4EGAA
SCHEMBL16900704 0.91 MEN1 (0.62) GPR3L3MBTL1NPSR1PTPRCCHEK1
SCHEMBL4934590 0.89 CA12 (0.53) GPR3L3MBTL1NPSR1KDM4EGAA
SCHEMBL29641986 0.89 CA12 (0.53) GPR3L3MBTL1NPSR1KDM4EGAA
SCHEMBL30827024 0.89 CA12 (0.53) GPR3L3MBTL1NPSR1KDM4EGAA
SCHEMBL5121583 0.88 GPR3 (0.64) GPR3L3MBTL1NPSR1KDM4EGAA
SCHEMBL5185936 0.86 CA12 (0.47) GPR3L3MBTL1NPSR1KDM4EGAA
SCHEMBL14174169 0.82 MAOA (0.47) GPR3L3MBTL1NPSR1KDM4EGAA
SCHEMBL29387122 0.80 GPR3 (1.00) GPR3L3MBTL1KDM4ECHEK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0342433-A2 Substituted dibenzothiaphenes AMERICAN CYANAMID COMPANY (US) 1989-11-23 EP claimed
EP-4263544-B1 INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE EMITTERS IN OLEDS UDC IRELAND LTD (IE) 2026-05-13 EP disclosed
EP-4676208-A2 NITROGEN-CONTAINING HETERO-AROMATICS FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2026-01-07 EP disclosed
US-20240101560-A1 NITROGENOUS HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES UDC IRELAND LIMITED (IE) 2024-03-28 US disclosed
WO-2022129113-A1 NITROGENOUS HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-06-23 WO disclosed
WO-2022129114-A1 NITROGENOUS COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-06-23 WO disclosed
WO-2022129116-A1 INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS MERCK PATENT GMBH (DE) 2022-06-23 WO disclosed
EP-3663300-B1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO LTD (KR) 2021-09-29 EP disclosed
US-8273769-B2 Phenoxy acetic acid derivatives MERCK SERONO SA (CH) 2012-09-25 US disclosed
EP-2396295-A1 PHENOXY ACETIC ACID DERIVATIVES Merck Serono S.A. (CH) 2011-12-21 EP disclosed
US-20110288066-A1 PHENOXY ACETIC ACID DERIVATIVES MERCK SERONO S.A. (CH) 2011-11-24 US disclosed
US-7910653-B2 Ionene polymers; for use in electrochemical cells; fuel cells; polymerization catalysts E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-03-22 US disclosed
US-7868086-B2 Arylene fluorinated sulfonimide polymers and membranes E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-01-11 US disclosed
US-7838612-B2 Arylene fluorinated sulfonimide compositions E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-11-23 US disclosed
WO-2010092043-A1 PHENOXY ACETIC ACID DERIVATIVES MERCK SERONO S.A. (CH) 2010-08-19 WO disclosed
US-20090136817-A1 ARYLENE FLUORINATED SULFONIMIDE POLYMERS AND MEMBRANES U.S. DEPARTMENT OF ENERGY 2009-05-28 US disclosed
US-20080214732-A1 PROCESS FOR THE PREPARATION OF ARYLENE FLUORINATED SULFONIMIDE POLYMERS AND MEMBRANES U.S. DEPARTMENT OF ENERGY 2008-09-04 US disclosed
US-20080177088-A1 ARYLENE FLUORINATED SULFONIMIDE COMPOSITIONS U.S. DEPARTMENT OF ENERGY 2008-07-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080177088-A1 ARYLENE FLUORINATED SULFONIMIDE COMPOSITIONS FES, FLNA, FLNB GPR3 3308/4885L3MBTL1 4840/4885NPSR1 2385/4885
US-20110288066-A1 PHENOXY ACETIC ACID DERIVATIVES HRH2, HRH1, HRH3 GPR3 434/4885L3MBTL1 4821/4885NPSR1 3017/4885
US-20240101560-A1 NITROGENOUS HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES NES, NCL, NPM1 GPR3 3926/4885L3MBTL1 2227/4885NPSR1 1275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.