Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL576031 | 0.79 | CCR2 (0.44) | SMN1; SMN2MAPK1CCR2ALDH1A1SIGMAR1 | |
| SCHEMBL577117 | 0.75 | MAPK1 (0.40) | SMN1; SMN2MAPK1CCR2POLBHTR7 | |
| SCHEMBL576483 | 0.70 | MAPK1 (0.44) | SMN1; SMN2MAPK1CCR2CHRM2CHRM4 | |
| SCHEMBL2485412 | 0.69 | GRM2 (0.49) | HTR7 | |
| SCHEMBL6081087 | 0.68 | MAPK1 (0.39) | SMN1; SMN2MAPK1ALDH1A1CHRM2CHRM4 | |
| SCHEMBL576540 | 0.67 | BRD4 (0.41) | SMN1; SMN2MAPK1CCR2ALDH1A1CHRM2 | |
| SCHEMBL10029146 | 0.67 | HCAR3 (0.37) | SMN1; SMN2MAPK1ALDH1A1CHRM2CHRM4 | |
| SCHEMBL19850785 | 0.67 | HCAR3 (0.37) | SMN1; SMN2MAPK1ALDH1A1CHRM2CHRM4 | |
| SCHEMBL11257113 | 0.65 | ALDH1A1 (0.38) | SMN1; SMN2MAPK1CCR2ALDH1A1CHRM2 | |
| SCHEMBL14350785 | 0.65 | MMP2 (0.40) | SMN1; SMN2MAPK1CCR2ALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239873-A1 | Phenyl-piperazine derivatives as modulators of muscarinic receptors | BLANCO MIGUEL GARCIA-GUZMAN | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239873-A1 | Phenyl-piperazine derivatives as modulators of muscarinic receptors | CHRM3, CHRM5, CHRM2 | SMN1; SMN2 4374/4885MAPK1 2519/4885CCR2 298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.