Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL520105 | 0.82 | MAPT (0.47) | KCNQ2ALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL23730151 | 0.80 | SRD5A1 (0.39) | KCNQ2ALDH1A1GAASMN1; SMN2HTT | |
| SCHEMBL26700312 | 0.80 | TDP1 (0.38) | ALDH1A1KDM4EGAASMN1; SMN2MAPT | |
| SCHEMBL15143883 | 0.77 | ACHE (0.42) | ALDH1A1KDM4EMAPTLMNAMEN1 | |
| SCHEMBL2616784 | 0.76 | NOTUM (0.58) | ALDH1A1KDM4EGAASMN1; SMN2F2 | |
| SCHEMBL22306381 | 0.75 | ALDH1A1 (0.39) | KCNQ2ALDH1A1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL154510 | 0.74 | CYP11B1 (0.52) | ALDH1A1GAAHTTNOTUMMAPT | |
| SCHEMBL18363028 | 0.74 | ALDH1A1 (0.44) | ALDH1A1KDM4EGAASMN1; SMN2F2 | |
| SCHEMBL434992 | 0.73 | ALDH1A1 (0.62) | ALDH1A1KDM4EGAAHTTNOTUM | |
| SCHEMBL5022145 | 0.72 | KMT2A (0.52) | ALDH1A1GAASMN1; SMN2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3097078-B1 | PYRIDINES AND PYRIMIDINES AND USE THEREOF | PURDUE PHARMA LP (US) | 2022-05-25 | — | — | EP | disclosed |
| US-20170008882-A1 | PYRIDINES AND PYRIMIDINES AND USE THEREOF | PURDUE PHARMA L.P. | 2017-01-12 | — | — | US | disclosed |
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | NPY1R, NPY5R, NPY2R | KCNQ2 587/4885ALDH1A1 4542/4885KDM4E 1604/4885 |
| US-20170008882-A1 | PYRIDINES AND PYRIMIDINES AND USE THEREOF | CACNA1A, P2RX3, P2RX6 | KCNQ2 69/4885ALDH1A1 658/4885KDM4E 1725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.