SCHEMBL13699124

SCHEMBL13699124

NS(=O)(=O)c1ccc(C(=O)NCCCCCNC(=O)c2cccc(S(=O)(=O)NCCCCCNC(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)c2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.52
KMT2A Q03164 2/20 0.49
LMNA P02545 1/20 0.49
RAB9A P51151 1/20 0.49
MAPK1 P28482 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
CCR2 P41597 1/20 0.49
CA1 P00915 5/20 0.47
ALDH1A1 P00352 2/20 0.47
NPSR1 Q6W5P4 1/20 0.47
NAMPT P43490 2/20 0.46
GAA P10253 1/20 0.46
TP53BP1 Q12888 1/20 0.46
HDAC3 O15379 2/20 0.46
HDAC1 Q13547 2/20 0.46
CA9 Q16790 3/20 0.45
CA7 P43166 2/20 0.45
CA14 Q9ULX7 1/20 0.45
POLB P06746 1/20 0.45
KDM4E B2RXH2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13699273 0.89 F2 (0.56) LMNARAB9AALDH1A1NPSR1NAMPT
SCHEMBL13699130 0.87 CA2 (0.66) CA2KMT2ACA1HDAC3HDAC1
SCHEMBL13699182 0.87 LMNA (0.48) LMNARAB9AALDH1A1NPSR1NAMPT
SCHEMBL13699232 0.83 CA2 (0.52) CA2CCR2CA1NAMPTTP53BP1
SCHEMBL13699284 0.81 CA2 (0.50) CA2CCR2CA1NAMPTTP53BP1
SCHEMBL13699282 0.79 CA2 (0.48) CA2CCR2CA1NAMPTHDAC3
SCHEMBL13699325 0.79 CA2 (0.48) CA2CCR2CA1NAMPTHDAC3
SCHEMBL13699125 0.78 RAB9A (0.51) LMNARAB9ANAMPTPOLB
SCHEMBL13699216 0.73 CA2 (0.62) CA2KMT2ACA1HDAC3HDAC1
SCHEMBL13699191 0.72 NAMPT (0.46) CA2LMNARAB9AALDH1A1NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009113704-A2 FLUORINE-CONTAINING COMPOUND AND METHOD FOR DETECTING BIOMOLECULE USING THE SAME KYOTO UNIVERSITY (JP) 2009-09-17 WO disclosed