Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 4/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4233751 | 0.89 | SLC5A7 (0.44) | OPRK1PGRAR | |
| SCHEMBL13699306 | 0.85 | SLC5A7 (0.44) | OPRK1PGRAR | |
| SCHEMBL4236439 | 0.80 | SLC5A7 (0.45) | OPRK1PGRARBRAF | |
| SCHEMBL4684561 | 0.78 | SLC5A7 (0.44) | OPRK1NPC1RAB9A | |
| SCHEMBL4233481 | 0.77 | HRH3 (0.47) | — | |
| SCHEMBL4238765 | 0.77 | HRH3 (0.47) | — | |
| SCHEMBL4238304 | 0.77 | SLC5A7 (0.41) | — | |
| SCHEMBL4232714 | 0.76 | SLC5A7 (0.45) | PGRARMCHR1 | |
| SCHEMBL4683501 | 0.74 | HRH3 (0.43) | MCHR1NPC1ALDH1A1TP53RAB9A | |
| SCHEMBL4232082 | 0.74 | HRH3 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |