Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | GAA | P10253 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 10/20 | 0.62 |
| ▸ | RAB9A | P51151 | 10/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | SNCA | P37840 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | MITF | O75030 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | APP | P05067 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL445048 | 0.92 | NPC1 (0.72) | MAPTALDH1A1GAANPC1RAB9A | |
| SCHEMBL31278127 | 0.85 | SMN1; SMN2 (0.60) | MAPTALDH1A1GAANPC1RAB9A | |
| SCHEMBL31278775 | 0.85 | SMN1; SMN2 (0.60) | MAPTALDH1A1GAANPC1RAB9A | |
| SCHEMBL31277640 | 0.84 | SMN1; SMN2 (0.60) | MAPTALDH1A1GAANPC1RAB9A | |
| SCHEMBL31278238 | 0.84 | SMN1; SMN2 (0.60) | MAPTALDH1A1GAANPC1RAB9A | |
| SCHEMBL16592509 | 0.82 | NPC1 (0.56) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL16592507 | 0.82 | NPC1 (0.56) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL16592611 | 0.82 | NPC1 (0.56) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL10892520 | 0.81 | KCNK3 (0.65) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10892514 | 0.81 | KCNK3 (0.65) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227762-A1 | NOVEL CATALYTIC MATERIALS AND THEIR USE IN THE PREPARATION OF POLYMERIC MATERIALS | UNIVERSITY OF LEEDS (GB) | 2009-09-10 | — | — | US | disclosed |
| US-20090227762-A1 | NOVEL CATALYTIC MATERIALS AND THEIR USE IN THE PREPARATION OF POLYMERIC MATERIALS | UNIVERSITY OF LEEDS (GB) | 2009-09-10 | — | — | US | disclosed |
| WO-2007052009-A1 | NOVEL CATALYTIC MATERIALS AND THEIR USE IN THE PREPARATION OF POLYMERIC MATERIALS | UNIVERSITY OF LEEDS (GB) | 2007-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227762-A1 | NOVEL CATALYTIC MATERIALS AND THEIR USE IN THE PREPARATION OF POLYMERIC MATERIALS | LDHA, LDHB, ALAD | MAPT 436/4885ALDH1A1 216/4885GAA 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.