Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.72 |
| ▸ | RAB9A | P51151 | 10/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.72 |
| ▸ | MAPT | P10636 | 6/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.72 |
| ▸ | GAA | P10253 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.72 |
| ▸ | RECQL | P46063 | 1/20 | 0.72 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | TP53 | P04637 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.71 |
| ▸ | MITF | O75030 | 2/20 | 0.71 |
| ▸ | SNCA | P37840 | 2/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | APP | P05067 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13699335 | 0.92 | MAPT (0.63) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11719648 | 0.82 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL16592903 | 0.82 | NPC1 (0.69) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6037590 | 0.82 | KDR (0.78) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL19476630 | 0.82 | NPC1 (0.71) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL231897 | 0.81 | KDR (0.78) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL28947571 | 0.80 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL29184186 | 0.80 | KDR (0.76) | NPC1RAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL1499654 | 0.80 | HTT (0.63) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL30132679 | 0.80 | MAPT (0.57) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770211-B | Alpha, beta unsaturated amide compound | 协和麒麟株式会社 | 2023-09-19 | — | — | CN | disclosed |
| EP-3792241-A1 | METHOD FOR CONVERTING HYDROXYL GROUP OF ALCOHOL | Takasago International Corporation (JP) | 2021-03-17 | — | — | EP | disclosed |
| US-20210047254-A1 | METHOD FOR CONVERTING HYDROXYL GROUP OF ALCOHOL | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2021-02-18 | — | — | US | disclosed |
| WO-2019216355-A1 | METHOD FOR CONVERTING HYDROXYL GROUP OF ALCOHOL | 高砂香料工業株式会社 (JP) | 2019-11-14 | — | — | WO | disclosed |
| CN-108430972-A | α, β unsaturated acyl amine compounds | 协和发酵麒麟株式会社 | 2018-08-21 | — | — | CN | disclosed |
| EP-2431353-B1 | Process for preparing amine compound | KANTO KAGAKU (JP) | 2016-01-20 | — | — | EP | disclosed |
| EP-2431353-A1 | Process for preparing amine compound | Kanto Kagaku Kabushiki Kaisha (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-20120065426-A1 | PROCESS FOR PREPARING AMINE COMPOUND | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065426-A1 | PROCESS FOR PREPARING AMINE COMPOUND | PNMT, HNMT, GNMT | NPC1 1818/4885RAB9A 1737/4885SMN1; SMN2 3579/4885 |
| US-20210047254-A1 | METHOD FOR CONVERTING HYDROXYL GROUP OF ALCOHOL | ADH1C, CBR1, NAP1L4 | NPC1 1736/4885RAB9A 2827/4885SMN1; SMN2 2863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.