Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CBFB | Q13951 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13700641 | 0.90 | KDM4E (0.45) | NPC1RAB9ALMNAKDM4EL3MBTL1 | |
| SCHEMBL30240912 | 0.84 | NPC1 (0.61) | NPC1RAB9ALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL76414 | 0.84 | NPC1 (0.61) | NPC1RAB9ALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL13700388 | 0.76 | NPC1 (0.43) | NPC1RAB9ALMNAKDM4EHTT | |
| SCHEMBL13699422 | 0.74 | KDM4E (0.40) | NPC1RAB9ALMNAKDM4EL3MBTL1 | |
| SCHEMBL11892463 | 0.73 | RAB9A (0.63) | NPC1RAB9ALMNAKDM4EGAA | |
| SCHEMBL29517159 | 0.73 | LMNA (0.58) | NPC1RAB9ALMNAKDM4EGAA | |
| SCHEMBL77763 | 0.73 | LMNA (0.58) | NPC1RAB9ALMNAKDM4EGAA | |
| SCHEMBL13700392 | 0.72 | NPC1 (0.47) | NPC1RAB9ALMNAKDM4EGAA | |
| SCHEMBL13699403 | 0.72 | NPC1 (0.43) | NPC1RAB9ALMNAKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2103445-B1 | Heat resistance improver and reversible thermosensitive recording medium | RICOH CO LTD (JP) | 2015-05-06 | — | — | EP | disclosed |
| US-8324399-B2 | Heat resistance improver and reversible thermosensitive recording medium | RICOH COMPANY, LTD. (JP) | 2012-12-04 | — | — | US | disclosed |
| US-20090239747-A1 | HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM | RICOH COMPANY, LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| EP-2103445-A1 | Heat resistance improver and reversible thermosensitive recording medium | Ricoh Company, Ltd. (JP) | 2009-09-23 | — | — | EP | disclosed |