SCHEMBL13699624

SCHEMBL13699624

CC(C)(C)OC(=O)COC(COCCOCCNC(=O)COC(COCCOCCN=[N+]=[N-])COCCOCCN=[N+]=[N-])COCCOCCNC(=O)COC(COCCOCCN=[N+]=[N-])COCCOCCN=[N+]=[N-]

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 0.33
CRBN Q96SW2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24864550 0.94 CRBN (0.33) APLNRCRBN
SCHEMBL13498592 0.90 APLNR (0.31) APLNR
SCHEMBL18385069 0.85 CRBN (0.33) CRBN
SCHEMBL13699608 0.83 APLNR (0.36) APLNR
SCHEMBL13699543 0.82 APLNR (0.36) APLNR
SCHEMBL3484881 0.81 APLNR (0.34) APLNR
SCHEMBL24864583 0.79 TLR2 (0.32) CRBN
SCHEMBL23418095 0.78 HDAC8 (0.40) CRBN
SCHEMBL24864549 0.77 TLR2 (0.37) APLNR
SCHEMBL17746975 0.77 HDAC8 (0.42) CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090240028-A1 Synthesis and Application of New Structural Well Defined Branched Polymers as Conjugating Agents for Peptides NOVO NORDISK A/S (DK) 2009-09-24 US disclosed
US-20090036353-A1 Insulin Derivatives Conjugated with Structurally Well Defined Branched Polymers NOVO NORDISK A/S (DK) 2009-02-05 US disclosed
US-20090036353-A1 Insulin Derivatives Conjugated with Structurally Well Defined Branched Polymers NOVO NORDISK A/S (DK) 2009-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090240028-A1 Synthesis and Application of New Structural Well Defined Branched Polymers as Conjugating Agents for Peptides VIP, PTMS, PDGFA APLNR 341/4885CRBN 1834/4885
US-20090036353-A1 Insulin Derivatives Conjugated with Structurally Well Defined Branched Polymers INSR, IAPP, IGF1R APLNR 771/4885CRBN 3533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.