SCHEMBL13699650

SCHEMBL13699650

c1ccc2c(c1)c1cnccc1n2CC1CCO1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.56
MAOB P27338 4/20 0.56
ACHE P22303 2/20 0.56
CYP2D6 P10635 1/20 0.49
IDO1 P14902 1/20 0.47
DHFR P00374 1/20 0.47
DDB1 Q16531 1/20 0.44
CRBN Q96SW2 1/20 0.44
TSHR P16473 2/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.42
LMNA P02545 1/20 0.42
KMT2A Q03164 1/20 0.42
GRIN1 Q05586 1/20 0.41
GRIN2A Q12879 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
PTGER4 P35408 1/20 0.40
MAPK1 P28482 1/20 0.40
HSD17B10 Q99714 1/20 0.40
HDAC3 O15379 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12727896 0.86 DHFR (0.59) DHFRTSHRKDM4EMEN1LMNA
SCHEMBL13699647 0.79 DHFR (0.60) MAOAMAOBACHECYP2D6IDO1
SCHEMBL19009222 0.73 MAOA (0.68) MAOAMAOBACHECYP2D6TSHR
SCHEMBL15380515 0.72 DHFR (0.79) CYP2D6DHFRTSHRKDM4EMEN1
SCHEMBL29558033 0.72 DHFR (0.79) CYP2D6DHFRTSHRKDM4EMEN1
SCHEMBL29558375 0.72 DHFR (0.79) CYP2D6DHFRTSHRKDM4EMEN1
SCHEMBL409180 0.72 DHFR (0.79) CYP2D6DHFRTSHRKDM4EMEN1
SCHEMBL15380522 0.72 DHFR (0.79) CYP2D6DHFRTSHRKDM4EMEN1
SCHEMBL30145441 0.72 DHFR (0.79) CYP2D6DHFRTSHRKDM4EMEN1
SCHEMBL27097159 0.71 MAOA (0.52) MAOAMAOBACHECYP2D6IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9130183-B2 Organic electroluminescent element, displaying device and lighting device Konica Minolta, Inc. (JP) 2015-09-08 US disclosed
US-9130183-B2 Organic electroluminescent element, displaying device and lighting device Konica Minolta, Inc. (JP) 2015-09-08 US disclosed
US-8758903-B2 Organic electroluminescent element, display device and lighting device KONICA MINOLTA HOLDINGS, INC. (JP) 2014-06-24 US disclosed
US-8758903-B2 Organic electroluminescent element, display device and lighting device KONICA MINOLTA HOLDINGS, INC. (JP) 2014-06-24 US disclosed
US-20090239000-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-09-24 US disclosed
US-20090239000-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-09-24 US disclosed
US-20090033213-A1 Organic Electroluminescent Element, Displaying Device and Lighting Device KONICA MINOLTA HOLDINGS, INC. (JP) 2009-02-05 US disclosed
US-20090033213-A1 Organic Electroluminescent Element, Displaying Device and Lighting Device KONICA MINOLTA HOLDINGS, INC. (JP) 2009-02-05 US disclosed