SCHEMBL13699647

SCHEMBL13699647

c1ccc2c(c1)c1ccncc1n2CC1CO1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.60
IDO1 P14902 1/20 0.55
MAOA P21397 4/20 0.48
MAOB P27338 4/20 0.48
ACHE P22303 2/20 0.48
MEN1 O00255 1/20 0.47
LMNA P02545 1/20 0.47
KMT2A Q03164 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
MAPT P10636 1/20 0.45
CYP2D6 P10635 1/20 0.42
HDAC2 Q92769 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
CYP1A2 P05177 1/20 0.39
CYP2C19 P33261 1/20 0.39
ROCK2 O75116 1/20 0.38
GRIN1 Q05586 1/20 0.38
GRIN2A Q12879 1/20 0.38
KCNH2 Q12809 1/20 0.36
DYRK1A Q13627 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15380515 0.85 DHFR (0.79) DHFRMEN1LMNAKMT2AL3MBTL1
SCHEMBL409180 0.85 DHFR (0.79) DHFRMEN1LMNAKMT2AL3MBTL1
SCHEMBL29558033 0.85 DHFR (0.79) DHFRMEN1LMNAKMT2AL3MBTL1
SCHEMBL15380522 0.85 DHFR (0.79) DHFRMEN1LMNAKMT2AL3MBTL1
SCHEMBL29558375 0.85 DHFR (0.79) DHFRMEN1LMNAKMT2AL3MBTL1
SCHEMBL30145441 0.85 DHFR (0.79) DHFRMEN1LMNAKMT2AL3MBTL1
SCHEMBL13699650 0.79 MAOA (0.56) DHFRIDO1MAOAMAOBACHE
SCHEMBL17517483 0.79 MAOA (0.67) IDO1MAOAMAOBACHEMEN1
SCHEMBL17517482 0.79 CYP1A2 (0.65) IDO1MAOAMAOBACHECYP2D6
SCHEMBL2220005 0.76 ALDH1A1 (0.55) IDO1MAOAMAOBACHEMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9130183-B2 Organic electroluminescent element, displaying device and lighting device Konica Minolta, Inc. (JP) 2015-09-08 US disclosed
US-9130183-B2 Organic electroluminescent element, displaying device and lighting device Konica Minolta, Inc. (JP) 2015-09-08 US disclosed
US-8758903-B2 Organic electroluminescent element, display device and lighting device KONICA MINOLTA HOLDINGS, INC. (JP) 2014-06-24 US disclosed
US-8758903-B2 Organic electroluminescent element, display device and lighting device KONICA MINOLTA HOLDINGS, INC. (JP) 2014-06-24 US disclosed
US-20090239000-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-09-24 US disclosed
US-20090239000-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-09-24 US disclosed
US-20090033213-A1 Organic Electroluminescent Element, Displaying Device and Lighting Device KONICA MINOLTA HOLDINGS, INC. (JP) 2009-02-05 US disclosed
US-20090033213-A1 Organic Electroluminescent Element, Displaying Device and Lighting Device KONICA MINOLTA HOLDINGS, INC. (JP) 2009-02-05 US disclosed