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SCHEMBL13699660

SCHEMBL13699660

FC(F)(F)c1cc(C(c2ccc(C(c3ccc(C(c4cc(C(F)(F)F)cc(C(F)(F)F)c4)c4cc(C(F)(F)F)cc(C(F)(F)F)c4)cc3)(C(F)(F)F)C(F)(F)F)cc2)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc(C(F)(F)F)c1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 1/20 0.42
▸ ESR2 Q92731 1/20 0.42
▸ CYP19A1 P11511 1/20 0.40
▸ CYP11B2 P19099 1/20 0.40
▸ IDO1 P14902 1/20 0.38
▸ TDO2 P48775 1/20 0.38
▸ CNR1 P21554 4/20 0.34
▸ CES2 O00748 2/20 0.33
▸ CES1 P23141 1/20 0.33
▸ TACR1 P25103 5/20 0.33
▸ PDE2A O00408 2/20 0.33
▸ PNMT P11086 1/20 0.32
▸ ACP3 P15309 1/20 0.32
▸ CACNA1F O60840 1/20 0.31
▸ CACNA1D Q01668 1/20 0.31
▸ CACNA1S Q13698 1/20 0.31
▸ CACNA1C Q13936 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25122169 0.88 CYP19A1 (0.47) CYP19A1CYP11B2IDO1TDO2CNR1
SCHEMBL4089231 0.81 CES2 (0.44) CYP19A1CYP11B2IDO1TDO2CES2
SCHEMBL13925398 0.81 CYP19A1 (0.40) ESR1ESR2CYP19A1CYP11B2IDO1
SCHEMBL2493440 0.76 CES2 (0.48) CES2CES1PDE2AACP3
SCHEMBL22278541 0.74 SLC2A1 (0.49) CYP19A1CYP11B2IDO1TDO2TACR1
SCHEMBL25121949 0.69 RAPGEF4 (0.44) CYP19A1CYP11B2IDO1TDO2CES2
SCHEMBL12937142 0.69 ESR1 (0.42) ESR1ESR2CES2TACR1
SCHEMBL7194676 0.69 KIF11 (0.50) ESR1ESR2
SCHEMBL16105865 0.69 ESR1 (0.50) ESR1ESR2IDO1PDE2A
SCHEMBL22874479 0.67 MEN1 (0.44) ESR1ESR2CYP19A1CYP11B2IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8758903-B2 Organic electroluminescent element, display device and lighting device KONICA MINOLTA HOLDINGS, INC. (JP) 2014-06-24 — — US disclosed
US-8758903-B2 Organic electroluminescent element, display device and lighting device KONICA MINOLTA HOLDINGS, INC. (JP) 2014-06-24 — — US disclosed
US-20090239000-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-09-24 — — US disclosed
US-20090239000-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-09-24 — — US disclosed