SCHEMBL2493440

SCHEMBL2493440

FC(F)(F)c1ccc(C(c2ccc(C(F)(F)F)cc2)c2ccc(C(F)(F)F)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.48
CES1 P23141 2/20 0.48
ALDH1A1 P00352 1/20 0.48
TSHR P16473 1/20 0.48
PDE2A O00408 1/20 0.47
KIF11 P52732 6/20 0.46
ACP3 P15309 1/20 0.45
ORAI1 Q96D31 1/20 0.44
ORAI2 Q96SN7 1/20 0.44
ORAI3 Q9BRQ5 1/20 0.44
TRPV6 Q9H1D0 1/20 0.44
MGLL Q99685 1/20 0.44
GSK3B P49841 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26438529 0.88 KIF11 (0.64) CES2CES1TSHRKIF11ACP3
SCHEMBL22402545 0.88 TRPV1 (0.46) CES2CES1ALDH1A1TSHRPDE2A
SCHEMBL25122169 0.88 CYP19A1 (0.47) CES2CES1ALDH1A1TSHRPDE2A
SCHEMBL31409220 0.88 KIF11 (0.64) CES2CES1ALDH1A1TSHRPDE2A
SCHEMBL20465824 0.88 PDE2A (0.44) CES2CES1ALDH1A1TSHRPDE2A
SCHEMBL13382016 0.84 KIF11 (0.68) ALDH1A1TSHRKIF11ACP3
SCHEMBL11540603 0.81 SLC6A3 (0.69) ALDH1A1TSHRKIF11ACP3
SCHEMBL63468 0.80 ALDH1A1 (0.67) CES2CES1ALDH1A1TSHRKIF11
SCHEMBL7643556 0.80 CES2 (0.47) CES2CES1ALDH1A1TSHRPDE2A
SCHEMBL26437522 0.79 KIF11 (0.53) CES2CES1TSHRPDE2AKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3475995-B1 QUANTUM DOT LIGHT EMITTING DEVICES DOW GLOBAL TECHNOLOGIES LLC (US) 2022-12-21 EP disclosed
US-20210210691-A1 POLYMERIC LAYER AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME. DOW GLOBAL TECHNOLOGIES LLC (US) 2021-07-08 US disclosed
US-10818860-B2 Quantum dot light emitting devices ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2020-10-27 US disclosed
US-20200066993-A1 POLYMERIC CHARGE TRANSFER LAYER AND ORGANIC ELECTRONIC DEVICE COMPRISING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2020-02-27 US disclosed
US-20190334106-A1 QUANTUM DOT LIGHT EMITTING DEVICES U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2019-10-31 US disclosed
US-10454036-B2 Polymeric charge transfer layer and organic electronic device containing the same DOW GLOBAL TECHNOLOGIES LLC (US) 2019-10-22 US disclosed
EP-2380567-B1 MELANIN PRODUCTION INHIBITOR POLA CHEM IND INC (JP) 2019-01-16 EP disclosed
US-20180226584-A1 POLYMERIC CHARGE TRANSFER LAYER AND ORGANIC ELECTRONIC DEVICE CONTAINING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2018-08-09 US disclosed
WO-2018089181-A1 ORGANIC INDOLYL TRIARYLAMINE COMPOUNDS AND ELECTRONIC DEVICES COMPRISING AN ORGANIC LAYER CONTAINING SUCH COMPOUNDS DOW GLOBAL TECHNOLOGIES LLC (US) 2018-05-17 WO disclosed
WO-2018089181-A1 ORGANIC INDOLYL TRIARYLAMINE COMPOUNDS AND ELECTRONIC DEVICES COMPRISING AN ORGANIC LAYER CONTAINING SUCH COMPOUNDS DOW GLOBAL TECHNOLOGIES LLC (US) 2018-05-17 WO disclosed
US-20110243865-A1 MELANIN PRODUCTION INHIBITOR POLA CHEMICAL INDUSTRIES INC. (JP) 2011-10-06 US disclosed
EP-2048168-A2 Process for producing catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer Sumitomo Chemical Company, Limited (JP) 2009-04-15 EP disclosed
EP-2048170-A2 Second catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer Sumitomo Chemical Company, Limited (JP) 2009-04-15 EP disclosed
EP-2048167-A2 First catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer Sumitomo Chemical Company, Limited (JP) 2009-04-15 EP disclosed
EP-2048169-A2 Third catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer Sumitomo Chemical Company, Limited (JP) 2009-04-15 EP disclosed
US-6914108-B2 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-07-05 US disclosed
US-20030203810-A1 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2003-10-30 US disclosed
US-6586356-B2 Coordination catalyst SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-07-01 US disclosed
US-20010020075-A1 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-09-06 US disclosed
EP-1113026-A2 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10454036-B2 Polymeric charge transfer layer and organic electronic device containing the same CLTB, CYBA, L1CAM CES2 1851/4885CES1 4809/4885ALDH1A1 1599/4885
US-20180226584-A1 POLYMERIC CHARGE TRANSFER LAYER AND ORGANIC ELECTRONIC DEVICE CONTAINING THE SAME CLTB, CYBA, L1CAM CES2 1851/4885CES1 4809/4885ALDH1A1 1599/4885
US-20110243865-A1 MELANIN PRODUCTION INHIBITOR TYR, F12, TH CES2 1159/4885CES1 1000/4885ALDH1A1 1292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.