Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA6 | P23280 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.47 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL710212 | 0.85 | LMNA (0.59) | LMNASMN1; SMN2GAAL3MBTL1CA1 | |
| SCHEMBL10154281 | 0.82 | LMNA (0.71) | LMNASMN1; SMN2GAAL3MBTL1CA1 | |
| SCHEMBL27438026 | 0.81 | LMNA (0.50) | LMNASMN1; SMN2GAAL3MBTL1CA1 | |
| SCHEMBL1369496 | 0.80 | LMNA (0.53) | LMNASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL1368170 | 0.80 | ALDH1A1 (0.49) | LMNAALDH1A1PNMT | |
| SCHEMBL6782609 | 0.79 | ALDH1A1 (0.48) | LMNASMN1; SMN2GAACA1CA2 | |
| SCHEMBL20767241 | 0.79 | CA1 (0.63) | LMNASMN1; SMN2GAAL3MBTL1CA1 | |
| SCHEMBL20779633 | 0.79 | CA1 (0.50) | LMNASMN1; SMN2GAAL3MBTL1CA1 | |
| SCHEMBL29909892 | 0.79 | CA1 (0.63) | LMNASMN1; SMN2GAAL3MBTL1CA1 | |
| SCHEMBL18578538 | 0.79 | VCAM1 (0.58) | LMNASMN1; SMN2GAAL3MBTL1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101863539-B | Methods and articles for maintaining hydantoinylated polymers in a biocidally active state | VANSON HALOSOURCE INC | 2015-02-18 | — | — | CN | disclosed |
| US-8722656-B2 | Cephalosporins useful as antibacterial agents | ZOETIS LLC (US) | 2014-05-13 | — | — | US | disclosed |
| EP-2705044-A1 | NOVEL CEPHALOSPORINS USEFUL AS ANTIBACTERIAL AGENTS | ZOETIS LLC (US) | 2014-03-12 | — | — | EP | disclosed |
| WO-2012150520-A1 | NOVEL CEPHALOSPORINS USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2012-11-08 | — | — | WO | disclosed |
| US-20120283237-A1 | NOVEL CEPHALOSPORINS USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2012-11-08 | — | — | US | disclosed |
| US-8273769-B2 | Phenoxy acetic acid derivatives | MERCK SERONO SA (CH) | 2012-09-25 | — | — | US | disclosed |
| US-20110288066-A1 | PHENOXY ACETIC ACID DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-11-24 | — | — | US | disclosed |
| EP-1678078-A1 | METHODS AND ARTICLES FOR MAINTAINING HYDANTOINYLATED POLYMERS IN A BIOCIDALLY ACTIVE STATE | Vanson Halosource, Inc. (US) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005033004-A1 | METHODS AND ARTICLES FOR MAINTAINING HYDANTOINYLATED POLYMERS IN A BIOCIDALLY ACTIVE STATE | VANSON HALOSOURCE, INC. (US) | 2005-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288066-A1 | PHENOXY ACETIC ACID DERIVATIVES | HRH2, HRH1, HRH3 | LMNA 4243/4885SMN1; SMN2 4361/4885GAA 722/4885 |
| US-20120283237-A1 | NOVEL CEPHALOSPORINS USEFUL AS ANTIBACTERIAL AGENTS | CIAPIN1, CLSPN, MRPL21 | LMNA 3599/4885SMN1; SMN2 3782/4885GAA 2991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.