Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.63 |
| ▸ | CA2 | P00918 | 7/20 | 0.63 |
| ▸ | CA9 | Q16790 | 5/20 | 0.63 |
| ▸ | CA12 | O43570 | 3/20 | 0.63 |
| ▸ | CA4 | P22748 | 3/20 | 0.63 |
| ▸ | CA6 | P23280 | 3/20 | 0.63 |
| ▸ | CA5A | P35218 | 3/20 | 0.63 |
| ▸ | CA7 | P43166 | 3/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.63 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 2/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.46 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20767241 | 1.00 | CA1 (0.63) | CA1CA2CA9CA12CA4 | |
| SCHEMBL3219444 | 0.83 | LMNA (0.59) | CA1CA2CA9CA12CA4 | |
| SCHEMBL3087579 | 0.81 | CA1 (0.58) | CA1CA2CA9CA12CA4 | |
| SCHEMBL27438026 | 0.79 | LMNA (0.50) | CA1CA2CA9CA12CA4 | |
| SCHEMBL1370060 | 0.79 | LMNA (0.65) | CA1CA2CA9CA12CA4 | |
| SCHEMBL10694524 | 0.79 | CA2 (0.70) | CA1CA2CA9CA12CA4 | |
| SCHEMBL29948313 | 0.79 | CA2 (0.70) | CA1CA2CA9CA12CA4 | |
| SCHEMBL11682482 | 0.79 | CA1 (0.59) | CA1CA2CA9CA12CA4 | |
| SCHEMBL878968 | 0.78 | CA2 (1.00) | CA1CA2CA9CA12CA4 | |
| SCHEMBL2811342 | 0.78 | CA2 (0.76) | CA1CA2CA9CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220267276-A1 | NLRP MODULATORS | NOVARTIS INFLAMMASOME RESEARCH, INC. | 2022-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220267276-A1 | NLRP MODULATORS | NLRP1, NRP1, NR4A3 | CA1 4067/4885CA2 2463/4885CA9 4279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.