SCHEMBL13700930

SCHEMBL13700930

O=c1oc(-c2n[nH]c3ccccc23)nc2ccccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.59
ALDH1A1 P00352 6/20 0.53
KDM4E B2RXH2 5/20 0.53
HPGD P15428 3/20 0.53
ALPL P05186 1/20 0.53
GAA P10253 1/20 0.53
IDO1 P14902 1/20 0.53
TTK P33981 1/20 0.53
MAPK10 P53779 1/20 0.53
C1R P00736 6/20 0.52
NPC1 O15118 4/20 0.52
RAB9A P51151 4/20 0.52
F2 P00734 3/20 0.52
KMT2A Q03164 2/20 0.52
NPSR1 Q6W5P4 1/20 0.52
PLG P00747 1/20 0.52
KLK1 P06870 1/20 0.52
PRSS1 P07477 1/20 0.52
C1S P09871 1/20 0.52
ATM Q13315 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL272287 0.80 ELANE (0.81) ELANEALDH1A1KDM4EHPGDC1R
SCHEMBL29791056 0.75 C1R (0.78) ELANEALDH1A1KDM4EHPGDC1R
SCHEMBL29456973 0.75 ELANE (0.93) ELANEALDH1A1KDM4EHPGDGAA
SCHEMBL125184 0.75 ELANE (0.93) ELANEALDH1A1KDM4EHPGDGAA
SCHEMBL9475884 0.75 C1R (0.78) ELANEALDH1A1KDM4EHPGDC1R
SCHEMBL2537274 0.75 ELANE (0.73) ELANEALDH1A1KDM4EHPGDC1R
SCHEMBL272702 0.75 ELANE (1.00) ELANEALDH1A1KDM4EHPGDC1R
SCHEMBL30914649 0.75 ELANE (0.73) ELANEALDH1A1KDM4EHPGDC1R
SCHEMBL29382161 0.75 ELANE (1.00) ELANEALDH1A1KDM4EHPGDC1R
SCHEMBL4796146 0.75 KDM4E (0.66) ALDH1A1KDM4EHPGDALPLGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090239982-A1 Ultraviolet Absorbent and Heterocyclic Compound FUJIFILM CORPORATION (JP) 2009-09-24 US disclosed
US-20090239982-A1 Ultraviolet Absorbent and Heterocyclic Compound FUJIFILM CORPORATION (JP) 2009-09-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090239982-A1 Ultraviolet Absorbent and Heterocyclic Compound CYP2A6, CYP2B6, XPO6 ELANE 1479/4885ALDH1A1 1360/4885KDM4E 2273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.