Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | IDO1 | P14902 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | ALPL | P05186 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | TTK | P33981 | 1/20 | 0.66 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.66 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.62 |
| ▸ | FLT1 | P17948 | 1/20 | 0.62 |
| ▸ | ITK | Q08881 | 5/20 | 0.53 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.51 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1672674 | 0.85 | IDO1 (0.78) | KDM4EIDO1ALDH1A1GAAALPL | |
| SCHEMBL30768403 | 0.79 | ALDH1A1 (1.00) | KDM4EIDO1ALDH1A1GAAALPL | |
| SCHEMBL855531 | 0.79 | ALDH1A1 (1.00) | KDM4EIDO1ALDH1A1GAAALPL | |
| SCHEMBL311148 | 0.77 | FGFR1 (1.00) | KDM4EIDO1ALDH1A1GAAALPL | |
| SCHEMBL29714859 | 0.77 | FGFR1 (1.00) | KDM4EIDO1ALDH1A1GAAALPL | |
| SCHEMBL17178615 | 0.76 | ALDH1A1 (0.92) | KDM4EIDO1ALDH1A1GAAALPL | |
| SCHEMBL29363709 | 0.75 | FGFR1 (0.55) | KDM4EIDO1ALDH1A1GAAALPL | |
| SCHEMBL2189184 | 0.75 | FGFR1 (0.55) | KDM4EIDO1ALDH1A1GAAALPL | |
| SCHEMBL13700930 | 0.75 | ELANE (0.59) | KDM4EIDO1ALDH1A1GAAALPL | |
| SCHEMBL3712544 | 0.74 | KDM4E (0.62) | KDM4EIDO1ALDH1A1GAAALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008041264-A1 | ISOINDOLO-QUINOXALINE DERIVATIVES HAVING ANTITUMOR ACTIVITY, PROCESS FOR THEIR PRODUCTION AND THEIR USE | UNIVERSITA' DEGLI STUDI DI PALERMO (IT) | 2008-04-10 | — | — | WO | disclosed |