SCHEMBL13700942

SCHEMBL13700942

O=c1oc(-c2nsc3ccccc23)nc2ccccc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 4/20 0.58
▸ C1R P00736 7/20 0.55
▸ KMT2A Q03164 4/20 0.55
▸ F2 P00734 4/20 0.55
▸ PLG P00747 1/20 0.55
▸ KLK1 P06870 1/20 0.55
▸ PRSS1 P07477 1/20 0.55
▸ C1S P09871 1/20 0.55
▸ ATM Q13315 1/20 0.55
▸ L3MBTL1 Q9Y468 1/20 0.55
▸ ALDH1A1 P00352 5/20 0.54
▸ HPGD P15428 3/20 0.54
▸ SMN1; SMN2 Q16637 3/20 0.54
▸ MEN1 O00255 2/20 0.54
▸ KDM4E B2RXH2 4/20 0.51
▸ NPC1 O15118 3/20 0.51
▸ RAB9A P51151 3/20 0.51
▸ NPSR1 Q6W5P4 2/20 0.51
▸ RXFP1 Q9HBX9 1/20 0.51
▸ MAPT P10636 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13701076 0.84 ELANE (0.47) ELANEC1RKMT2AF2PLG
SCHEMBL272287 0.79 ELANE (0.81) ELANEC1RKMT2AF2PLG
SCHEMBL29791056 0.77 C1R (0.78) ELANEC1RKMT2AF2PLG
SCHEMBL9475884 0.77 C1R (0.78) ELANEC1RKMT2AF2PLG
SCHEMBL9475739 0.76 C1R (0.76) ELANEC1RKMT2AF2PLG
SCHEMBL18963257 0.76 C1R (0.76) ELANEC1RKMT2AF2PLG
SCHEMBL13700932 0.75 ELANE (0.59) ELANEC1RKMT2AF2PLG
SCHEMBL13700930 0.75 ELANE (0.59) ELANEC1RKMT2AF2PLG
SCHEMBL2537274 0.74 ELANE (0.73) ELANEC1RKMT2AF2PLG
SCHEMBL272702 0.74 ELANE (1.00) ELANEC1RKMT2AF2PLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090239982-A1 Ultraviolet Absorbent and Heterocyclic Compound FUJIFILM CORPORATION (JP) 2009-09-24 — — US disclosed
US-20090239982-A1 Ultraviolet Absorbent and Heterocyclic Compound FUJIFILM CORPORATION (JP) 2009-09-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090239982-A1 Ultraviolet Absorbent and Heterocyclic Compound CYP2A6, CYP2B6, XPO6 ELANE 1479/4885C1R 520/4885KMT2A 2903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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