Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | ERN1 | O75460 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1611920 | 0.82 | CYP2A6 (0.55) | ALDH1A1TSHRMCL1CYP1A2CYP2A6 | |
| SCHEMBL8038001 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TSHRTRIM24TRIM33MCL1 | |
| SCHEMBL13563990 | 0.78 | CYP1A2 (0.50) | ALDH1A1TSHRMCL1CYP1A2KMT2A | |
| SCHEMBL12811472 | 0.78 | CYP1A2 (0.50) | ALDH1A1TSHRMCL1CYP1A2KMT2A | |
| SCHEMBL787917 | 0.76 | MAOA (0.44) | ALDH1A1TSHRTRIM24TRIM33KMT2A | |
| SCHEMBL29957919 | 0.74 | ALDH1A1 (0.60) | ALDH1A1TSHRTRIM24TRIM33MCL1 | |
| SCHEMBL12143563 | 0.74 | ALDH1A1 (0.60) | ALDH1A1TSHRTRIM24TRIM33MCL1 | |
| SCHEMBL9379369 | 0.74 | MCL1 (0.52) | ALDH1A1MCL1CYP1A2CYP2A6LMNA | |
| SCHEMBL12799811 | 0.74 | MCL1 (0.47) | ALDH1A1MCL1CYP1A2CYP2A6PRKDC | |
| SCHEMBL1320093 | 0.74 | ALDH1A1 (0.39) | ALDH1A1TSHRTRIM24TRIM33CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239982-A1 | Ultraviolet Absorbent and Heterocyclic Compound | FUJIFILM CORPORATION (JP) | 2009-09-24 | — | — | US | disclosed |
| US-20090239982-A1 | Ultraviolet Absorbent and Heterocyclic Compound | FUJIFILM CORPORATION (JP) | 2009-09-24 | — | — | US | disclosed |
| US-20080319175-A1 | Transthyretin Stabilization | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239982-A1 | Ultraviolet Absorbent and Heterocyclic Compound | CYP2A6, CYP2B6, XPO6 | ALDH1A1 1360/4885TSHR 3028/4885TRIM24 2886/4885 |
| US-20080319175-A1 | Transthyretin Stabilization | TTR, TTPA, ALB | ALDH1A1 525/4885TSHR 1379/4885TRIM24 1620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.