SCHEMBL1370103

SCHEMBL1370103

CCCCc1cc[c]c2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.36
TLR8 Q9NR97 1/20 0.35
CNR2 P34972 4/20 0.35
BCHE P06276 1/20 0.35
MAPT P10636 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
TYR P14679 1/20 0.33
PTPN1 P18031 1/20 0.33
PARP1 P09874 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2257428 0.93 LIPG (0.45) LIPGTLR8MAPTCYP3A4TYR
SCHEMBL2251371 0.93 LIPG (0.45) LIPGTLR8MAPTCYP3A4TYR
SCHEMBL5750515 0.93 LIPG (0.45) LIPGTLR8MAPTCYP3A4TYR
SCHEMBL1368599 0.89 KDM4E (0.36) CNR2
SCHEMBL1371874 0.88 BCHE (0.36) LIPGTLR8BCHE
SCHEMBL9162717 0.84 TSHR (0.35) BCHEMAPTCYP3A4CYP2C9
SCHEMBL1975122 0.83 LIPG (0.41) LIPGTLR8
SCHEMBL2247387 0.81 LIPG (0.44) LIPGTLR8MAPT
SCHEMBL2252287 0.81 LIPG (0.44) LIPGTLR8MAPT
SCHEMBL5746577 0.81 LIPG (0.44) LIPGTLR8MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023038077-A1 INKJET PRINTING METHOD 日本化薬株式会社 2023-03-16 WO disclosed
US-10451967-B2 Acid- and radical-generating agent and method for generating acid and radical FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2019-10-22 US disclosed
WO-2018158150-A1 TREATMENT OF DEMENTIA WITH CANNABINOID AGONISTS UNIVERSIDAD DEL PAÍS VASCO/EUSKAL HERRIKO UNIBERTSITATEA (ES) 2018-09-07 WO disclosed
EP-2818462-B1 CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMISCENT ELEMENT CONTAINING THESE AS COMPONENT TOSOH CORP (JP) 2017-11-08 EP disclosed
US-9624193-B2 Cyclic azine derivatives, processes for producing these, and organic electroluminescent element containing these as component TOSOH CORPORATION (JP) 2017-04-18 US disclosed
US-20160342084-A1 ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2016-11-24 US disclosed
US-9469662-B2 Process for preparing optically active biophosphinylalkanes BASF SE (DE) 2016-10-18 US disclosed
EP-2746271-B1 Phenyl-substituted 1, 3, 5-triazine compounds as intermediates for electroluminescent molecules TOSOH CORP (JP) 2016-08-17 EP disclosed
CN-105764885-A Acid- and radical-generating agent and method for generating acid and radical 和光纯药工业株式会社 2016-07-13 CN disclosed
US-20150329544-A1 CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THESE AS COMPONENT TOSOH CORPORATION (JP) 2015-11-19 US disclosed
WO-2007012655-A1 PROCESS FOR PREPARING OPTICALLY ACTIVE DIPHOSPHANES BASF SE (DE) 2007-02-01 WO disclosed
EP-1411912-A1 TREATMENT OF CHRONIC PAIN WITH 3-ARYLOXY-3-PHENYLPROPANAMINES PHARMACIA & UPJOHN COMPANY (US) 2004-04-28 EP disclosed
EP-1411934-A1 TREATMENT OF CHRONIC PAIN WITH 3-HETEROCYCLYL- AND 3-CYCLOALKYL-3-ARYLOXYPROPANAMINES PHARMACIA & UPJOHN COMPANY (US) 2004-04-28 EP disclosed
US-20030087965-A1 Treatment of chronic pain with 3-aryloxy-3-phenylpropanamines PHARMACIA & UPJOHN COMPANY 2003-05-08 US disclosed
US-20030087938-A1 Treatment of chronic pain with 3-heterocycloxy-and 3-cycloalkyloxy-3-phenylpropanamines PHARMACIA & UPJOHN COMPANY 2003-05-08 US disclosed
WO-2003011272-A1 TREATMENT OF CHRONIC PAIN WITH 3-ARYLOXY-3-PHENYLPROPANAMINES PHARMACIA & UPJOHN COMPANY (US) 2003-02-13 WO disclosed
WO-2003011289-A1 TREATMENT OF CHRONIC PAIN WITH 3-HETEROCYCLYL- AND 3-CYCLOALKYL-3-ARYLOXYPROPANAMINES PHARMACIA + UPJOHN COMPANY (US) 2003-02-13 WO disclosed
US-RE31388-E ORGANOSILANE COATING, BARIUM ALLOY, METAL CAPABLE OF EXOTHERMIC REACTION SAES GETTERS, S.P.A. (IT) 1983-09-20 US disclosed
US-4139537-A 3-Aryloxy-1-(2- or 4-iminodihydro-1-pyridyl)-2-propanol antiarrhythmic compounds COOPER LABORATORIES, INC. (US) 1979-02-13 US disclosed
US-4127361-A BARIUM ALLOY, ORGANO-SILANE COATING S.A.E.S. GETTERS S.P.A. (IT) 1978-11-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10451967-B2 Acid- and radical-generating agent and method for generating acid and radical CBR1, HAO2, CBR3 LIPG 3948/4885TLR8 2695/4885CNR2 915/4885
US-20160342084-A1 ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL CBR1, HAO2, CBR3 LIPG 3948/4885TLR8 2695/4885CNR2 915/4885
US-20150329544-A1 CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THESE AS COMPONENT CPNE4, EPB41, AZI2 LIPG 3208/4885TLR8 4656/4885CNR2 3846/4885
US-20030087965-A1 Treatment of chronic pain with 3-aryloxy-3-phenylpropanamines PNMT, OPRL1, OPRK1 LIPG 4459/4885TLR8 1673/4885CNR2 7/4885
US-20030087938-A1 Treatment of chronic pain with 3-heterocycloxy-and 3-cycloalkyloxy-3-phenylpropanamines OPRK1, CNR2, OPRL1 LIPG 4232/4885TLR8 1627/4885CNR2 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.