Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.55 |
| ▸ | MEN1 | O00255 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 6/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL924596 | 0.76 | RORC (0.56) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL14199692 | 0.73 | MAPT (0.82) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL25179738 | 0.73 | NPSR1 (0.68) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL13705490 | 0.72 | ALDH1A1 (0.54) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL2852620 | 0.72 | NPSR1 (0.67) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL7722815 | 0.71 | NPSR1 (1.00) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL11052440 | 0.71 | CYP3A4 (0.48) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL4727871 | 0.71 | MAPT (1.00) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL1593423 | 0.71 | MAPT (0.79) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL6979660 | 0.71 | NPSR1 (0.66) | MAPTMEN1KMT2ANPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592374-B2 | Insecticidal nitromethylene compounds | CROMPTON CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |
| US-7592374-B2 | Insecticidal nitromethylene compounds | CROMPTON CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |