SCHEMBL13707239

SCHEMBL13707239

Cl[Si](Cl)(Cl)CCCCCc1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 7/20 0.42
KCNH2 Q12809 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CHRM2 P08172 1/20 0.40
HTR1A P08908 1/20 0.40
ADRA2A P08913 1/20 0.40
CHRM1 P11229 1/20 0.40
DRD1 P21728 1/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
ADRA1A P35348 1/20 0.40
OPRM1 P35372 1/20 0.40
DRD3 P35462 1/20 0.40
SLC6A3 Q01959 1/20 0.40
MAOB P27338 2/20 0.39
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3688326 0.93 KCNH2 (0.42) SIGMAR1KCNH2MEN1KMT2ACHRM2
SCHEMBL1316206 0.93 KCNH2 (0.42) SIGMAR1KCNH2MEN1KMT2ACHRM2
SCHEMBL1304308 0.89 HSD11B1 (0.39) KCNH2MEN1KMT2ACHRM2HTR1A
SCHEMBL2872396 0.86 KCNH2 (0.34) KCNH2MEN1KMT2ACHRM2HTR1A
SCHEMBL5488263 0.84 SIGMAR1 (0.52) SIGMAR1MAOBMAPTL3MBTL1MAOA
SCHEMBL5482754 0.84 SIGMAR1 (0.52) SIGMAR1MAOBMAPTL3MBTL1MAOA
SCHEMBL18979256 0.84 SIGMAR1 (0.52) SIGMAR1MAOBMAPTL3MBTL1MAOA
SCHEMBL29118253 0.84 SIGMAR1 (0.52) SIGMAR1MAOBMAPTL3MBTL1MAOA
SCHEMBL574732 0.84 SIGMAR1 (0.52) SIGMAR1MAOBMAPTL3MBTL1MAOA
SCHEMBL3791482 0.84 SIGMAR1 (0.52) SIGMAR1MAOBMAPTL3MBTL1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7591699-B2 Method of manufacturing light-emitting element including the emission layer and the carrier transfer layer SEIKO EPSON CORPORATION (JP) 2009-09-22 US disclosed