SCHEMBL5482754

SCHEMBL5482754

Cl[Si](Cl)(Cl)CCCCCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 11/20 0.52
MAOA P21397 1/20 0.50
MAPT P10636 1/20 0.48
RXFP1 Q9HBX9 1/20 0.48
MAOB P27338 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5488263 1.00 SIGMAR1 (0.52) SIGMAR1MAOAMAPTRXFP1MAOB
SCHEMBL29118253 1.00 SIGMAR1 (0.52) SIGMAR1MAOAMAPTRXFP1MAOB
SCHEMBL3791482 1.00 SIGMAR1 (0.52) SIGMAR1MAOAMAPTRXFP1MAOB
SCHEMBL18979256 1.00 SIGMAR1 (0.52) SIGMAR1MAOAMAPTRXFP1MAOB
SCHEMBL574732 1.00 SIGMAR1 (0.52) SIGMAR1MAOAMAPTRXFP1MAOB
SCHEMBL1203381 0.98 MAOA (0.52) SIGMAR1MAOAMAPTRXFP1MAOB
SCHEMBL1599233 0.91 SIGMAR1 (0.48) SIGMAR1MAOAMAOBL3MBTL1
SCHEMBL13707239 0.84 SIGMAR1 (0.42) SIGMAR1MAOAMAPTMAOBL3MBTL1
SCHEMBL16207822 0.83 SIGMAR1 (0.50) SIGMAR1MAOAMAPTRXFP1MAOB
SCHEMBL10000437 0.83 SIGMAR1 (0.50) SIGMAR1MAOAMAPTRXFP1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180219160-A1 BENZOBIS(THIADIAZOLE) DERIVATIVE, INK COMPRISING THE SAME, AND ORGANIC ELECTRONIC DEVICE USING THE SAME UBE INDUSTRIES, LTD. (JP) 2018-08-02 US disclosed
EP-3181569-A1 BENZOBIS(THIADIAZOLE) DERIVATIVE, INK CONTAINING SAME, AND ORGANIC ELECTRONIC DEVICE USING SAME UBE Industries, Ltd. (JP) 2017-06-21 EP disclosed
CN-106661057-A Benzobis(thiadiazole) derivative, ink containing same, and organic electronic device using same 宇部兴产株式会社 2017-05-10 CN disclosed
US-9303049-B2 Nanodot and method for manufacturing the same NATIONAL SUN YAT-SEN UNIVERSITY (TW) 2016-04-05 US disclosed
US-20150073167-A1 NANODOT AND METHOD FOR MANUFACTURING THE SAME NATIONAL SUN YAT-SEN UNIVERSITY (TW) 2015-03-12 US disclosed
US-8207529-B2 Thin film transistor and flat panel display having the thin film transistor SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-06-26 US disclosed
US-20100308317-A1 THIN FILM TRANSISTOR, METHOD OF MANUFACTURING THE SAME AND FLAT PANEL DISPLAY HAVING THE THIN FILM TRANSISTOR SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-12-09 US disclosed
US-7799597-B2 Thin film transistor, method of manufacturing the same and flat panel display having the thin film transistor SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-09-21 US disclosed
US-7291747-B2 Silicon compounds and process for preparation thereof CHISSO CORPORATION (JP) 2007-11-06 US disclosed
US-20070090362-A1 Thin film transistor, method of manufacturing the same and flat panel display having the thin film transistor SAMSUNG SDI CO., LTD. (KR) 2007-04-26 US disclosed
US-20040143081-A1 Novel silicon compounds and process for preparation thereof JNC CORPORATION (JP) 2004-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180219160-A1 BENZOBIS(THIADIAZOLE) DERIVATIVE, INK COMPRISING THE SAME, AND ORGANIC ELECTRONIC DEVICE USING THE SAME IKZF3, HELZ, TEC SIGMAR1 3454/4885MAOA 815/4885MAPT 2949/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.