Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | INMT | O95050 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13709189 | 0.86 | ALDH1A1 (0.43) | HRH3ALOX12ALDH1A1MEN1KMT2A | |
| SCHEMBL9015889 | 0.82 | ALOX12 (0.41) | HRH3ALOX12ALDH1A1MEN1KMT2A | |
| SCHEMBL9015996 | 0.80 | ALOX12 (0.50) | HRH3ALOX12ALDH1A1MEN1KMT2A | |
| SCHEMBL19603145 | 0.80 | HRH3 (0.51) | HRH3ALOX12ALDH1A1MEN1KMT2A | |
| SCHEMBL11842202 | 0.76 | HRH3 (0.51) | HRH3ALOX12ALDH1A1MEN1KMT2A | |
| SCHEMBL27158578 | 0.76 | HRH3 (0.51) | HRH3ALOX12ALDH1A1MEN1KMT2A | |
| SCHEMBL30487782 | 0.76 | HRH3 (0.48) | HRH3ALOX12ALDH1A1MEN1KMT2A | |
| SCHEMBL20769599 | 0.76 | HRH3 (0.48) | HRH3ALOX12ALDH1A1MEN1KMT2A | |
| SCHEMBL29977549 | 0.75 | HRH3 (0.50) | HRH3ALOX12ALDH1A1MEN1KMT2A | |
| SCHEMBL27158593 | 0.75 | HRH3 (0.50) | HRH3ALOX12ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2096109-A1 | CARBOXYLIC ACID DERIVATIVE | Astellas Pharma Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |