Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13709223 | 0.80 | HRH3 (0.48) | ALOX12CES1HTR2CALDH1A1MEN1 | |
| SCHEMBL13709189 | 0.78 | ALDH1A1 (0.43) | ALOX12CES1ALDH1A1MEN1KMT2A | |
| SCHEMBL9015889 | 0.77 | ALOX12 (0.41) | ALOX12CES1ALDH1A1MEN1KMT2A | |
| SCHEMBL2625788 | 0.75 | ALOX12 (0.60) | ALOX12CES1HTR2CALDH1A1MEN1 | |
| SCHEMBL24358931 | 0.74 | ALOX12 (0.42) | ALOX12CES1HTR2CALDH1A1MEN1 | |
| SCHEMBL11837962 | 0.74 | RAB9A (0.47) | ALOX12CES1HTR2CALDH1A1MEN1 | |
| SCHEMBL20348492 | 0.74 | ALOX12 (0.42) | ALOX12CES1HTR2CALDH1A1MEN1 | |
| SCHEMBL3312853 | 0.74 | CES1 (0.44) | ALOX12CES1HTR2CALDH1A1MEN1 | |
| SCHEMBL2625802 | 0.74 | NOTUM (0.50) | ALOX12CES1HTR2CALDH1A1MEN1 | |
| SCHEMBL24308956 | 0.73 | ALDH1A1 (0.47) | ALOX12CES1HTR2CALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441222-B1 | Process and electrode system for determining an analyte or an oxidoreductase as well as suitable compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1996-12-18 | — | — | EP | disclosed |
| EP-0441222-A2 | Process and electrode system for determining an analyte or an oxidoreductase as well as suitable compounds | Roche Diagnostics GmbH (DE) | 1991-08-14 | — | — | EP | disclosed |