Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13709189 | 0.83 | ALDH1A1 (0.43) | ALOX12CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL13709223 | 0.82 | HRH3 (0.48) | ALOX12CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9015996 | 0.77 | ALOX12 (0.50) | ALOX12ALDH1A1MEN1KMT2ACES1 | |
| SCHEMBL1450283 | 0.70 | ALDH1A1 (0.68) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL29555396 | 0.70 | ALDH1A1 (0.68) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL38653591 | 0.69 | DRD3 (0.55) | — | |
| SCHEMBL142527 | 0.69 | MAPT (0.48) | ALDH1A1MEN1KMT2AGAAMAPT | |
| Hydrochloric Acid SCHEMBL9015908 | 0.68 | NOS3 (0.47) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL28519973 | 0.66 | HDAC6 (0.53) | ALOX12CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL5253343 | 0.66 | ALDH1A1 (0.60) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441222-B1 | Process and electrode system for determining an analyte or an oxidoreductase as well as suitable compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1996-12-18 | — | — | EP | disclosed |
| EP-0441222-A2 | Process and electrode system for determining an analyte or an oxidoreductase as well as suitable compounds | Roche Diagnostics GmbH (DE) | 1991-08-14 | — | — | EP | disclosed |