Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | CTSV | O60911 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1368894 | 0.85 | LPL (0.37) | NPC1RAB9AKDM4EKCNH2SMN1; SMN2 | |
| SCHEMBL1370764 | 0.82 | HSD11B1 (0.47) | TP53NPC1RAB9AKDM4ECTSV | |
| SCHEMBL2228477 | 0.80 | HRH3 (0.58) | KDM4ETAAR1MAPK1L3MBTL1 | |
| SCHEMBL8081767 | 0.80 | HSD11B1 (0.49) | TP53EGFRRAB9AKDM4EKCNH2 | |
| SCHEMBL1775198 | 0.80 | TRPA1 (0.44) | TAAR1ALDH1A1 | |
| SCHEMBL9029706 | 0.80 | TAAR1 (0.54) | TP53CYP2A6NPC1KDM4ETAAR1 | |
| SCHEMBL6609575 | 0.80 | TSHR (0.44) | LMNA | |
| SCHEMBL3639347 | 0.79 | BCL2 (0.42) | TP53CYP2A6CYP1A2NPC1RAB9A | |
| SCHEMBL3742259 | 0.79 | MEN1 (0.39) | CYP2A6TAAR1NFKB1MAPTLMNA | |
| Ethylamine SCHEMBL27831005 | 0.78 | TAAR1 (0.35) | TP53CYP2A6NPC1RAB9ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6888022-B2 | Methods and compounds for inhibiting β-amyloid peptide release and/or its synthesis | ATHENA NEUROSCIENCES, INC. (US) | 2005-05-03 | — | — | US | claimed |
| EP-1423386-A1 | THIOPHENYLTHIOPYRANE DIOXIDES AS MMP OR TNF-ALPHA INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-02 | — | — | EP | claimed |
| US-20030229024-A1 | Methods and compounds for inhibiting beta-amyloid peptide release and/or its synthesis | AUDIA JAMES E (US) | 2003-12-11 | — | — | US | claimed |
| WO-2003022842-A1 | THIOPHENYLTHIOPYRANE DIOXIDES AS MMP OR TNF-ALPHA INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-20 | — | — | WO | claimed |
| US-20020052322-A1 | Methods and compounds for inhibiting beta-amyloid peptide release and/or its synthesis | ELAN PHARMACEUTICALS, INC. | 2002-05-02 | — | — | US | claimed |
| US-6191166-B1 | ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. | 2001-02-20 | — | — | US | claimed |
| CN-1238779-A | Methods and compounds for inhibiting beta-amyloid peptide release and/or its synthesis | ELAN PHARM INC (US) | 1999-12-15 | — | — | CN | claimed |
| EP-0942924-A2 | METHODS AND COMPOUNDS FOR INHIBITING $g(b)-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS | Elan Pharmaceuticals, Inc. (US) | 1999-09-22 | — | — | EP | claimed |
| WO-1998022494-A9 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | — | 1998-08-20 | — | — | WO | claimed |
| WO-1998022494-A2 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | ELAN PHARMACEUTICALS, INC. (US) | 1998-05-28 | — | — | WO | claimed |
| CN-116034147-B | Adhesive composition containing antistatic agent and surface protective film | 株式会社LG化学 | 2024-04-05 | — | — | CN | disclosed |
| US-20230323171-A1 | ADHESIVE COMPOSITION CONTAINING ANTISTATIC AGENT AND SURFACE PROTECTIVE FILM | XINMEI FONTANA HOLDING (HONG KONG) LIMITED (CN) | 2023-10-12 | — | — | US | disclosed |
| EP-4190877-A1 | ADHESIVE COMPOSITION CONTAINING ANTISTATIC AGENT AND SURFACE PROTECTIVE FILM | Lg Chem, Ltd. (KR) | 2023-06-07 | — | — | EP | disclosed |
| CN-116034147-A | Adhesive composition containing antistatic agent and surface protective film | 株式会社LG化学 | 2023-04-28 | — | — | CN | disclosed |
| CN-112996876-B | Adhesive composition, surface protective film, and method for manufacturing organic light-emitting electronic device | 株式会社LG化学 | 2023-04-18 | — | — | CN | disclosed |
| EP-0707585-A1 | BICYCLIC TETRAHYDRO PYRAZOLOPYRIDINES | PFIZER INC. (US) | 1996-04-24 | — | — | EP | disclosed |
| WO-1995001980-A1 | BICYCLIC TETRAHYDRO PYRAZOLOPYRIDINES | PFIZER INC. (US) | 1995-01-19 | — | — | WO | disclosed |
| EP-0407877-A2 | 1,2-Dihaloazolylethane derivatives and fungicides containing them | BASF Aktiengesellschaft (DE) | 1991-01-16 | — | — | EP | disclosed |
| US-4524168-A | AZO DYES | CIBA-GEIGY CORPORATION (US) | 1985-06-18 | — | — | US | disclosed |
| EP-0001937-B1 | PROCESS FOR THE HYDROCARBONYLATION OF METHANOL TO ETHANOL IN THE PRESENCE OF AN INERT LIQUID | The British Petroleum Company p.l.c. (GB) | 1981-09-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052322-A1 | Methods and compounds for inhibiting beta-amyloid peptide release and/or its synthesis | APP, BACE1, IAPP | TP53 1452/4885CYP2A6 3470/4885CYP1A2 4192/4885 |
| US-20030229024-A1 | Methods and compounds for inhibiting beta-amyloid peptide release and/or its synthesis | APP, BACE1, IAPP | TP53 1452/4885CYP2A6 3470/4885CYP1A2 4192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.