Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.53 |
| ▸ | CCR1 | P32246 | 1/20 | 0.50 |
| ▸ | CCR5 | P51681 | 1/20 | 0.50 |
| ▸ | CCR8 | P51685 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.48 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.48 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.48 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.47 |
| ▸ | PIM1 | P11309 | 2/20 | 0.47 |
| ▸ | CLK2 | P49760 | 2/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27062709 | 0.81 | PDGFRB (0.54) | CYP1A2PDGFRBPDGFRACYP2A6ALDH1A1 | |
| SCHEMBL18812500 | 0.80 | PDGFRB (0.61) | CYP1A2PDGFRBPDGFRACYP2A6CCR1 | |
| SCHEMBL12386954 | 0.79 | CYP1A2 (0.62) | CYP1A2PDGFRBPDGFRACYP2A6CCR1 | |
| SCHEMBL16805027 | 0.78 | CCR1 (0.55) | CYP1A2CYP2A6CCR1CCR5CCR8 | |
| SCHEMBL29378350 | 0.77 | BIRC5 (0.66) | CYP1A2PDGFRBPDGFRACYP2A6ALDH1A1 | |
| SCHEMBL15344108 | 0.77 | BIRC5 (0.66) | CYP1A2PDGFRBPDGFRACYP2A6ALDH1A1 | |
| SCHEMBL32667946 | 0.76 | PDGFRB (0.77) | CYP1A2PDGFRBPDGFRACYP2A6ALDH1A1 | |
| SCHEMBL2772360 | 0.76 | PDGFRB (0.77) | CYP1A2PDGFRBPDGFRACYP2A6ALDH1A1 | |
| SCHEMBL23555381 | 0.76 | PDGFRB (0.66) | CYP1A2PDGFRBPDGFRACYP2A6ALDH1A1 | |
| SCHEMBL8370258 | 0.76 | PDGFRB (0.66) | CYP1A2PDGFRBPDGFRACYP2A6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221591-A1 | Selective Inhibitors of Human Corticosteroid Synthases | UNIVERSITAT DES SAARLANDES (DE) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221591-A1 | Selective Inhibitors of Human Corticosteroid Synthases | CYP11B1, HSD11B1, HSD17B1 | CYP1A2 38/4885PDGFRB 2920/4885PDGFRA 4093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.