Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 8/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2733186 | 0.87 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNASMN1; SMN2HPGD | |
| SCHEMBL2733616 | 0.84 | ALDH1A1 (0.41) | ALDH1A1LMNASMN1; SMN2HPGDNPC1 | |
| SCHEMBL2733197 | 0.77 | RAB9A (0.45) | ALDH1A1MAPTSMN1; SMN2HPGDNPC1 | |
| SCHEMBL2733030 | 0.69 | MAP2K1 (0.44) | LMNASMN1; SMN2ARMEN1KMT2A | |
| SCHEMBL13713684 | 0.68 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL14424854 | 0.67 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNASMN1; SMN2HPGD | |
| SCHEMBL8351467 | 0.65 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNASMN1; SMN2HPGD | |
| SCHEMBL4836303 | 0.65 | KDM4E (0.34) | ALDH1A1HPGD | |
| SCHEMBL4088527 | 0.64 | GAA (0.43) | ALDH1A1LMNASMN1; SMN2HPGDNPC1 | |
| SCHEMBL30590411 | 0.64 | TRPA1 (0.38) | ALDH1A1LMNASMN1; SMN2ARMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044008-A2 | 2 -AMINOTHIOPHENE COMPOUNDS AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-05-19 | — | — | WO | disclosed |