Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 12/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.51 |
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13714615 | 0.91 | DHODH (0.57) | GHSRDHODH | |
| SCHEMBL14429911 | 0.90 | GHSR (0.70) | GHSREPHX1ALDH1A1HTTADRB3 | |
| SCHEMBL11592875 | 0.90 | DHODH (0.56) | GHSRDHODH | |
| SCHEMBL11596260 | 0.87 | GHSR (0.63) | GHSREPHX1ALDH1A1HTTADRB3 | |
| SCHEMBL13724331 | 0.82 | GHSR (0.51) | GHSREPHX1ALDH1A1HTTEPHX2 | |
| SCHEMBL2237869 | 0.79 | TIMP3 (0.55) | GHSR | |
| SCHEMBL6074124 | 0.79 | GHSR (0.67) | GHSREPHX1ALDH1A1HTTADRB3 | |
| SCHEMBL8788507 | 0.79 | CA2 (0.70) | GHSREPHX1ALDH1A1HTTADRB3 | |
| SCHEMBL7095018 | 0.79 | GHSR (0.67) | GHSREPHX1ALDH1A1HTTADRB3 | |
| SCHEMBL11034317 | 0.78 | EPHX1 (0.84) | GHSREPHX1ALDH1A1HTTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579339-B2 | Ring-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-08-25 | — | — | US | disclosed |
| US-7579339-B2 | Ring-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-08-25 | — | — | US | disclosed |