Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 5/20 | 0.51 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2237869 | 0.91 | TIMP3 (0.55) | GHSRTIMP3KDM4EL3MBTL1PRMT1 | |
| SCHEMBL11596260 | 0.84 | GHSR (0.63) | GHSREPHX1ALDH1A1HTTEPHX2 | |
| SCHEMBL14429911 | 0.84 | GHSR (0.70) | GHSREPHX1ALDH1A1HTTEPHX2 | |
| SCHEMBL13723547 | 0.83 | CASR (0.58) | KDM4ECA2EPHX1ALDH1A1HTT | |
| SCHEMBL13714744 | 0.82 | GHSR (0.58) | GHSREPHX1ALDH1A1HTTEPHX2 | |
| SCHEMBL10192080 | 0.80 | ALDH1A1 (0.64) | L3MBTL1CA2EPHX1ALDH1A1HTT | |
| SCHEMBL29348883 | 0.80 | CNR1 (0.60) | CA2ALDH1A1CA12CA1CA4 | |
| SCHEMBL4624732 | 0.80 | FOLH1 (0.52) | KDM4ECA2EPHX1ALDH1A1HTT | |
| SCHEMBL8549863 | 0.79 | GHSR (0.49) | GHSRTIMP3KDM4ECA2EPHX1 | |
| SCHEMBL2234743 | 0.79 | EPHX1 (0.68) | KDM4EEPHX1ALDH1A1HTTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012142698-A1 | ALKYLUREA DERIVATIVES ACTIVE AGAINST CANCER CELLS | UNIVERSITE LAVAL (CA) | 2012-10-26 | — | — | WO | disclosed |