Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | POLA1 | P09884 | 1/20 | 0.32 |
| ▸ | POLG | P54098 | 1/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.30 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3857077 | 0.91 | FDPS (0.40) | FDPSABCB11POLA1POLGFAP | |
| SCHEMBL13714861 | 0.90 | FAP (0.41) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL13714841 | 0.88 | HSP90AA1 (0.33) | — | |
| SCHEMBL13714868 | 0.86 | — | — | |
| SCHEMBL6004916 | 0.83 | FDPS (0.36) | FDPSFGFR1FGFR4 | |
| SCHEMBL3852186 | 0.80 | SLC22A6 (0.46) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL13715042 | 0.80 | ABCB11 (0.32) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL3854698 | 0.79 | HPRT1 (0.40) | SLC22A6FGFR1 | |
| SCHEMBL13714795 | 0.78 | NT5E (0.33) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL3853999 | 0.77 | SLC22A12 (0.31) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579332-B2 | Nucleobase phosphonate analogs for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2009-08-25 | — | — | US | disclosed |