Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 16/20 | 0.41 |
| ▸ | NOS2 | P35228 | 11/20 | 0.41 |
| ▸ | NOS3 | P29474 | 9/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11982706 | 0.78 | SIGMAR1 (0.47) | NOS1NOS2 | |
| SCHEMBL1157243 | 0.78 | NOS1 (0.53) | NOS1NOS2NOS3 | |
| SCHEMBL14028969 | 0.78 | NOS1 (0.36) | NOS1NOS2NOS3CHRNA7 | |
| SCHEMBL10134884 | 0.78 | NOS1 (0.58) | NOS1NOS2NOS3 | |
| SCHEMBL8440754 | 0.78 | TSHR (0.46) | NOS1NOS2NOS3CHRNA7 | |
| SCHEMBL8439706 | 0.78 | TRPA1 (0.42) | NOS1NOS2NOS3CHRNA7 | |
| SCHEMBL31182115 | 0.78 | CYP3A4 (0.44) | NOS1NOS2NOS3CHRNA7 | |
| SCHEMBL7019980 | 0.78 | CYP3A4 (0.44) | NOS1NOS2NOS3CHRNA7 | |
| SCHEMBL28254036 | 0.78 | IDO1 (0.36) | NOS1NOS2NOS3 | |
| SCHEMBL657613 | 0.77 | CALM1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465880-B1 | 5-SULPHANYL-4H-1,2,4-TRIAZOLE DERIVATIVES AND THEIR USE TO TREAT DISORDERS ASSOCIATED WITH SOMATOSTATINE | IPSEN PHARMA (FR) | 2009-08-05 | — | — | EP | disclosed |