Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | F3 | P13726 | 5/20 | 0.45 |
| ▸ | F7 | P08709 | 4/20 | 0.45 |
| ▸ | F2 | P00734 | 3/20 | 0.45 |
| ▸ | F10 | P00742 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13716053 | 0.80 | KMT2A (0.45) | KMT2AGAAHSD17B10HPGDF3 | |
| SCHEMBL6348347 | 0.73 | F2 (0.55) | KMT2AGAAHSD17B10HPGDF3 | |
| SCHEMBL162726 | 0.72 | MLYCD (0.65) | KMT2AGAAHSD17B10HPGDKDM4E | |
| SCHEMBL7665736 | 0.70 | F3 (0.51) | KMT2AGAAHSD17B10HPGDF3 | |
| SCHEMBL7652022 | 0.70 | F3 (0.48) | KMT2AGAAHSD17B10HPGDF3 | |
| SCHEMBL18434389 | 0.70 | HPGD (0.77) | KMT2AGAAHSD17B10HPGDKDM4E | |
| SCHEMBL161881 | 0.70 | KMT2A (0.81) | KMT2AGAAHSD17B10HPGDKDM4E | |
| SCHEMBL15921303 | 0.69 | MAPK14 (0.45) | HPGDMAPK14ACSS2 | |
| SCHEMBL17865783 | 0.68 | MLYCD (0.73) | KMT2AGAAHSD17B10HPGDKDM4E | |
| SCHEMBL19657222 | 0.68 | TAS1R3 (0.62) | KMT2AGAAHSD17B10HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383731-B1 | BIARYL COMPOUNDS AS SERINE PROTEASE INHIBITORS | BIOCRYST PHARM INC (US) | 2009-08-05 | — | — | EP | disclosed |