Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12755657 | 0.85 | PAX8 (0.43) | NPC1RAB9AMEN1KMT2AGAA | |
| SCHEMBL27948249 | 0.85 | ALDH1A1 (0.41) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20612658 | 0.84 | NPC1 (0.54) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL15044749 | 0.84 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2ACA1 | |
| SCHEMBL14453125 | 0.78 | NPC1 (0.58) | NPC1RAB9AMEN1KMT2ACA1 | |
| SCHEMBL12867 | 0.77 | NPC1 (0.64) | NPC1RAB9AMEN1KMT2AGAA | |
| SCHEMBL28879276 | 0.76 | LMNA (0.46) | NPC1RAB9AKMT2ACA1CA2 | |
| SCHEMBL9492626 | 0.76 | NPC1 (0.68) | NPC1RAB9AMEN1KMT2AGAA | |
| SCHEMBL14679448 | 0.74 | ALDH1A1 (0.66) | NPC1RAB9AMEN1KMT2AGAA | |
| SCHEMBL1753828 | 0.73 | L3MBTL1 (0.71) | NPC1RAB9AMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572301-B2 | Fibre-reactive dyes, their preparation and their use | HUNTSMAN INTERNATIONAL LLC (US) | 2009-08-11 | — | — | US | disclosed |
| US-20080250575-A1 | Fibre-Reactive Dyes, Their Preparation And Their Use | HUNTSMAN INTERNATIONAL LLC | 2008-10-16 | — | — | US | disclosed |