Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | GLP1R | P43220 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13720913 | 0.89 | ALDH1A1 (0.46) | ALDH1A1KMT2ASMN1; SMN2LMNATSHR | |
| SCHEMBL13858509 | 0.81 | CHRNA7 (0.42) | CHRNA7CCR5ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL13721204 | 0.80 | OGFRL1 (0.39) | ALDH1A1SMN1; SMN2LMNATSHRHTT | |
| SCHEMBL13721202 | 0.80 | OGFRL1 (0.39) | ALDH1A1SMN1; SMN2LMNATSHRHTT | |
| SCHEMBL13720349 | 0.80 | HPGD (0.37) | ALDH1A1KMT2ASMN1; SMN2LMNATSHR | |
| SCHEMBL13721432 | 0.78 | LMNA (0.50) | KMT2ASMN1; SMN2LMNACNR2POLB | |
| SCHEMBL13720957 | 0.78 | SMN1; SMN2 (0.47) | ALDH1A1KMT2ASMN1; SMN2LMNATSHR | |
| SCHEMBL13721811 | 0.76 | KDM4E (0.46) | ALDH1A1KMT2ALMNAHTTL3MBTL1 | |
| SCHEMBL13721614 | 0.73 | ALOX15 (0.42) | ALDH1A1KMT2ASMN1; SMN2LMNATSHR | |
| SCHEMBL1791098 | 0.69 | ALDH1A1 (0.45) | ALDH1A1KMT2ASMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120289500-A1 | POTASSIUM CHANNEL MODULATORS | ABBOTT LABORATORIES (US) | 2012-11-15 | — | — | US | claimed |
| US-8859549-B2 | Potassium channel modulators | ABBVIE, INC. (US) | 2014-10-14 | — | — | US | disclosed |
| US-20120289500-A1 | POTASSIUM CHANNEL MODULATORS | ABBOTT LABORATORIES (US) | 2012-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120289500-A1 | POTASSIUM CHANNEL MODULATORS | KCNQ1, KCNQ2, KCNJ2 | CHRNA7 169/4885CCR5 4194/4885ALDH1A1 743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.