Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 9/20 | 0.57 |
| ▸ | MMP8 | P22894 | 9/20 | 0.57 |
| ▸ | MMP1 | P03956 | 2/20 | 0.57 |
| ▸ | MMP3 | P08254 | 2/20 | 0.57 |
| ▸ | ACE | P12821 | 2/20 | 0.56 |
| ▸ | ECE1 | P42892 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | APAF1 | O14727 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 8/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.49 |
| ▸ | ADAM12 | O43184 | 1/20 | 0.49 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.49 |
| ▸ | MMP7 | P09237 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13723565 | 0.93 | ECE1 (0.60) | MMP9MMP8MMP1MMP3ACE | |
| SCHEMBL21929715 | 0.86 | ACE (0.61) | MMP9MMP8MMP1MMP3ACE | |
| SCHEMBL26025173 | 0.83 | GHSR (0.56) | ACEECE1KDM4EMAPT | |
| SCHEMBL26169713 | 0.83 | ECE1 (0.66) | MMP9MMP8MMP1MMP3ACE | |
| SCHEMBL16301507 | 0.83 | ECE1 (0.66) | MMP9MMP8MMP1MMP3ACE | |
| SCHEMBL21955437 | 0.83 | ACE (0.72) | MMP9MMP8MMP1MMP3ACE | |
| SCHEMBL26444796 | 0.82 | MMP8 (0.56) | MMP9MMP8MMP1MMP3ACE | |
| SCHEMBL21929523 | 0.81 | ECE1 (0.63) | MMP9MMP8MMP1MMP3ACE | |
| SCHEMBL22330622 | 0.79 | KDM4E (0.52) | MMP9MMP8MMP1MMP3ACE | |
| SCHEMBL7678071 | 0.79 | KDM4E (0.67) | MMP9MMP8MMP1MMP3ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203581-A1 | Novel Peptides for Use in the Treatment of Obesity | NOVO NORDISK A/S (DK) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203581-A1 | Novel Peptides for Use in the Treatment of Obesity | MC4R, MC3R, GIPR | MMP9 2748/4885MMP8 1915/4885MMP1 2674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.