Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 7/20 | 0.56 |
| ▸ | MMP2 | P08253 | 6/20 | 0.56 |
| ▸ | MMP9 | P14780 | 5/20 | 0.56 |
| ▸ | MMP1 | P03956 | 3/20 | 0.56 |
| ▸ | MMP7 | P09237 | 1/20 | 0.56 |
| ▸ | ECE1 | P42892 | 6/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26169713 | 0.90 | ECE1 (0.66) | MMP8MMP2MMP9MMP1MMP7 | |
| SCHEMBL16301507 | 0.90 | ECE1 (0.66) | MMP8MMP2MMP9MMP1MMP7 | |
| SCHEMBL26444811 | 0.87 | MMP1 (0.54) | MMP8MMP2MMP9MMP1MMP7 | |
| SCHEMBL21929715 | 0.85 | ACE (0.61) | MMP8MMP2MMP9MMP1ECE1 | |
| SCHEMBL21929523 | 0.84 | ECE1 (0.63) | MMP8MMP2MMP9MMP1ECE1 | |
| SCHEMBL13723039 | 0.82 | MMP9 (0.57) | MMP8MMP2MMP9MMP1MMP7 | |
| SCHEMBL8357549 | 0.81 | MMP8 (0.57) | MMP8MMP2MMP9MMP1MMP7 | |
| SCHEMBL8358360 | 0.81 | MMP2 (0.59) | MMP8MMP2MMP9MMP1MMP7 | |
| SCHEMBL8354772 | 0.81 | MMP2 (0.59) | MMP8MMP2MMP9MMP1MMP7 | |
| SCHEMBL21955437 | 0.80 | ACE (0.72) | MMP8MMP9MMP1ECE1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230128688-A1 | DIRECTED CONJUGATION TECHNOLOGIES | KLEO PHARMACEUTICALS, INC. | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230128688-A1 | DIRECTED CONJUGATION TECHNOLOGIES | CD2BP2, CD2, CD47 | MMP8 1244/4885MMP2 1511/4885MMP9 2922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.