Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 7/20 | 0.66 |
| ▸ | ACE | P12821 | 2/20 | 0.62 |
| ▸ | MMP9 | P14780 | 7/20 | 0.61 |
| ▸ | MMP8 | P22894 | 7/20 | 0.61 |
| ▸ | MMP1 | P03956 | 3/20 | 0.61 |
| ▸ | MMP3 | P08254 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | APAF1 | O14727 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | MMP2 | P08253 | 7/20 | 0.59 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.59 |
| ▸ | ADAM12 | O43184 | 1/20 | 0.59 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.59 |
| ▸ | MMP7 | P09237 | 1/20 | 0.59 |
| ▸ | MMP12 | P39900 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.59 |
| ▸ | MMP14 | P50281 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26169713 | 1.00 | ECE1 (0.66) | ECE1ACEMMP9MMP8MMP1 | |
| SCHEMBL26444796 | 0.90 | MMP8 (0.56) | ECE1ACEMMP9MMP8MMP1 | |
| SCHEMBL21955437 | 0.88 | ACE (0.72) | ECE1ACEMMP9MMP8MMP1 | |
| SCHEMBL21929715 | 0.87 | ACE (0.61) | ECE1ACEMMP9MMP8MMP1 | |
| SCHEMBL7854107 | 0.84 | KDM4E (0.70) | ECE1ACEMMP9MMP8MMP1 | |
| SCHEMBL13074475 | 0.83 | ECE1 (0.54) | ECE1MMP9MMP8MMP1MMP3 | |
| SCHEMBL26168931 | 0.83 | POLB (0.62) | ECE1ACEMMP9MMP8MMP1 | |
| SCHEMBL13723039 | 0.83 | MMP9 (0.57) | ECE1ACEMMP9MMP8MMP1 | |
| SCHEMBL24915375 | 0.83 | ACE (0.67) | ECE1ACEMMP9MMP8MMP1 | |
| SCHEMBL16656724 | 0.83 | ECE1 (0.67) | ECE1ACEMMP9MMP8MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110313136-A1 | IgG-Fc FRAGMENT AND PROCESS FOR PRODUCING THE SAME | OTSUKA CHEMICAL CO., LTD. (JP) | 2011-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110313136-A1 | IgG-Fc FRAGMENT AND PROCESS FOR PRODUCING THE SAME | FCGR1A, FCGR2A, FCGR3B | ECE1 4199/4885ACE 3398/4885MMP9 4522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.