Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | NNMT | P40261 | 2/20 | 0.43 |
| ▸ | CTSG | P08311 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.42 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 3/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13724650 | 0.95 | KDM4A (0.46) | KDM4ACACNA1BNNMTCTSGITGB3 | |
| SCHEMBL13725569 | 0.94 | PLAU (0.46) | KDM4ACACNA1BNNMTCTSGITGB3 | |
| SCHEMBL13725576 | 0.94 | KDM4A (0.49) | KDM4ACACNA1BNNMTCTSGITGB3 | |
| SCHEMBL13725586 | 0.92 | KDM4A (0.49) | KDM4ACACNA1BNNMTCTSGITGB3 | |
| SCHEMBL13724136 | 0.92 | NNMT (0.48) | KDM4ACACNA1BNNMTCTSGITGB3 | |
| SCHEMBL12293625 | 0.92 | NNMT (0.48) | KDM4ACACNA1BNNMTCTSGITGB3 | |
| SCHEMBL12293481 | 0.91 | NNMT (0.47) | KDM4ACACNA1BNNMTCTSGITGB3 | |
| SCHEMBL13724891 | 0.91 | NNMT (0.47) | KDM4ACACNA1BNNMTCTSGITGB3 | |
| SCHEMBL13724286 | 0.91 | NNMT (0.46) | KDM4ACACNA1BNNMTCTSGITGB3 | |
| SCHEMBL13723864 | 0.91 | NNMT (0.46) | KDM4ACACNA1BNNMTCTSGITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8076285-B2 | Lysobactin amides | AICURIS GMBH & CO. KG (DE) | 2011-12-13 | — | — | US | disclosed |
| US-8076285-B2 | Lysobactin amides | AICURIS GMBH & CO. KG (DE) | 2011-12-13 | — | — | US | disclosed |
| US-20090203582-A1 | LYSOBACTIN AMIDES | BAYER HEALTHCARE AG (DE) | 2009-08-13 | — | — | US | disclosed |
| US-20090203582-A1 | LYSOBACTIN AMIDES | BAYER HEALTHCARE AG (DE) | 2009-08-13 | — | — | US | disclosed |
| WO-2007118691-A1 | LYSOBACTIN AMIDES | AICURIS GMBH & CO. KG (DE) | 2007-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203582-A1 | LYSOBACTIN AMIDES | AADAT, HAMP, DLST | KDM4A 1460/4885CACNA1B 3490/4885NNMT 870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.