Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13727381 | 0.90 | HTT (0.43) | POLBTP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13727503 | 0.88 | NAAA (0.46) | SMN1; SMN2HPGDKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL13728407 | 0.75 | HPGD (0.50) | ERCC1FEN1ERCC4TP53EGLN1 | |
| SCHEMBL15458806 | 0.74 | EGLN1 (0.65) | ERCC1FEN1ERCC4TP53EGLN1 | |
| SCHEMBL13824143 | 0.74 | POLB (0.46) | ERCC1FEN1ERCC4POLBTP53 | |
| SCHEMBL15680149 | 0.73 | POLB (0.44) | ERCC1FEN1ERCC4POLBTP53 | |
| SCHEMBL5461694 | 0.72 | EGLN1 (0.51) | POLBEGLN1SMN1; SMN2CYP1A2 | |
| SCHEMBL13729263 | 0.72 | L3MBTL1 (0.47) | EGLN1SMN1; SMN2HPGDKDM4EALDH1A1 | |
| SCHEMBL13729514 | 0.72 | L3MBTL1 (0.47) | EGLN1SMN1; SMN2HPGDKDM4EALDH1A1 | |
| SCHEMBL13823951 | 0.70 | GABRG2 (0.51) | ERCC1FEN1ERCC4POLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151567-A1 | PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2012-11-08 | — | — | WO | disclosed |