Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 4/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13729514 | 1.00 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1LMNASMN1; SMN2NAAA | |
| SCHEMBL13727503 | 0.85 | NAAA (0.46) | L3MBTL1ALDH1A1LMNASMN1; SMN2NAAA | |
| SCHEMBL13727448 | 0.84 | NAAA (0.44) | L3MBTL1ALDH1A1LMNASMN1; SMN2NAAA | |
| SCHEMBL13727381 | 0.79 | HTT (0.43) | L3MBTL1ALDH1A1LMNASMN1; SMN2NAAA | |
| SCHEMBL30545066 | 0.72 | EPHX1 (0.57) | L3MBTL1ALDH1A1LMNASMN1; SMN2NAAA | |
| SCHEMBL13727136 | 0.72 | ERCC1 (0.42) | L3MBTL1ALDH1A1SMN1; SMN2EGLN1HPGD | |
| SCHEMBL31347372 | 0.71 | EGLN1 (0.61) | ALDH1A1LMNASMN1; SMN2EGLN1HPGD | |
| SCHEMBL13729337 | 0.71 | NAAA (0.49) | ALDH1A1SMN1; SMN2NAAAHPGDKDM4E | |
| SCHEMBL17580836 | 0.70 | NAAA (0.54) | L3MBTL1ALDH1A1LMNASMN1; SMN2NAAA | |
| SCHEMBL21496535 | 0.70 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1LMNASMN1; SMN2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151567-A1 | PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2012-11-08 | — | — | WO | disclosed |