Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 15/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 14/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.63 |
| ▸ | NCOR2 | Q9Y618 | 6/20 | 0.63 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.57 |
| ▸ | CDC25A | P30304 | 1/20 | 0.49 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11061872 | 1.00 | HDAC1 (0.63) | HDAC1HDAC3HDAC2NCOR2HDAC10 | |
| SCHEMBL3871501 | 0.93 | HDAC1 (0.55) | HDAC1HDAC3HDAC2NCOR2HDAC10 | |
| SCHEMBL13728016 | 0.86 | ALDH1A1 (0.64) | HDAC1HDAC3HDAC2NCOR2HDAC10 | |
| SCHEMBL24327215 | 0.86 | HDAC3 (0.58) | HDAC1HDAC3HDAC2NCOR2HDAC10 | |
| SCHEMBL6247309 | 0.84 | HDAC3 (0.53) | HDAC1HDAC3HDAC2NCOR2HDAC10 | |
| SCHEMBL8720375 | 0.84 | HDAC3 (0.53) | HDAC1HDAC3HDAC2NCOR2HDAC10 | |
| SCHEMBL215272 | 0.82 | HDAC3 (0.50) | HDAC1HDAC3HDAC2NCOR2HDAC10 | |
| SCHEMBL7940066 | 0.82 | ALDH1A1 (0.50) | HDAC1HDAC3HDAC2NCOR2HDAC10 | |
| SCHEMBL5518973 | 0.81 | ALDH1A1 (0.76) | HDAC1HDAC3HDAC2NCOR2HDAC10 | |
| SCHEMBL5514066 | 0.81 | ALDH1A1 (0.76) | HDAC1HDAC3HDAC2NCOR2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077781-A1 | FLAVIN DERIVATIVES | GADWOOD ROBERT (US) | 2012-03-29 | — | — | US | disclosed |
| EP-2320734-A1 | FLAVIN DERIVATIVES | BioRelix, Inc. (US) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010019208-A1 | FLAVIN DERIVATIVES | BIORELIX PHARMACEUTICALS, INC. (US) | 2010-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077781-A1 | FLAVIN DERIVATIVES | BLVRB, FLAD1, FDPS | HDAC1 3088/4885HDAC3 2627/4885HDAC2 2916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.