Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 15/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 14/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.63 |
| ▸ | NCOR2 | Q9Y618 | 6/20 | 0.63 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.57 |
| ▸ | CDC25A | P30304 | 1/20 | 0.49 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL863993 | 1.00 | HDAC1 (0.63) | HDAC1HDAC3HDAC2NCOR2HDAC10 | |
| SCHEMBL3871501 | 0.93 | HDAC1 (0.55) | HDAC1HDAC3HDAC2NCOR2HDAC10 | |
| SCHEMBL13728016 | 0.86 | ALDH1A1 (0.64) | HDAC1HDAC3HDAC2NCOR2HDAC10 | |
| SCHEMBL24327215 | 0.86 | HDAC3 (0.58) | HDAC1HDAC3HDAC2NCOR2HDAC10 | |
| SCHEMBL6247309 | 0.84 | HDAC3 (0.53) | HDAC1HDAC3HDAC2NCOR2HDAC10 | |
| SCHEMBL8720375 | 0.84 | HDAC3 (0.53) | HDAC1HDAC3HDAC2NCOR2HDAC10 | |
| SCHEMBL215272 | 0.82 | HDAC3 (0.50) | HDAC1HDAC3HDAC2NCOR2HDAC10 | |
| SCHEMBL7940066 | 0.82 | ALDH1A1 (0.50) | HDAC1HDAC3HDAC2NCOR2HDAC10 | |
| SCHEMBL5518973 | 0.81 | ALDH1A1 (0.76) | HDAC1HDAC3HDAC2NCOR2HDAC10 | |
| SCHEMBL5514066 | 0.81 | ALDH1A1 (0.76) | HDAC1HDAC3HDAC2NCOR2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4433094-A | BUTADIENE-STYRENE COPOLYMER AND DIENE RUBBER, CARBON BLACK AND VULCANIZATION AGENT | BRIDGESTONE TIRE COMPANY LIMITED (JP) | 1984-02-21 | — | — | US | disclosed |