Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DHPS | P49366 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12335699 | 0.84 | KDM4E (0.52) | KDM4EALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL8352524 | 0.84 | ALDH1A1 (0.52) | KDM4EALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL1536392 | 0.82 | ALDH1A1 (0.50) | KDM4EALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL13730392 | 0.79 | MAPK1 (0.33) | KDM4EALDH1A1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL13728298 | 0.79 | L3MBTL1 (0.41) | KDM4EALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL13728967 | 0.79 | MAPT (0.41) | KDM4EALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL2879866 | 0.76 | POLB (0.68) | KDM4EALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL3932873 | 0.76 | KDM4E (0.47) | KDM4EALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL52405 | 0.74 | ALDH1A1 (1.00) | KDM4EALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL29366129 | 0.74 | ALDH1A1 (1.00) | KDM4EALDH1A1SMN1; SMN2MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103732613-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-11-30 | — | — | CN | disclosed |
| CN-103797024-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-06-01 | — | — | CN | disclosed |
| CN-103562199-B | As the tripeptides mixing deuterium of hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-03-30 | — | — | CN | disclosed |
| EP-2909205-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2015-08-26 | — | — | EP | disclosed |
| CN-103797024-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2014-05-14 | — | — | CN | disclosed |
| WO-2014062196-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-04-24 | — | — | WO | disclosed |
| CN-103732613-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2014-04-16 | — | — | CN | disclosed |
| EP-2705049-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2014-03-12 | — | — | EP | disclosed |
| CN-103562199-A | Tripeptides incorporating deuterium as inhibitors of hepatitis c virus | BRISTOL MYERS SQUIBB CO | 2014-02-05 | — | — | CN | disclosed |
| WO-2012151195-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-11-08 | — | — | WO | disclosed |