Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 12/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26317676 | 0.76 | PDE10A (0.43) | PDE10ATRPA1PDGFRBPDGFRA | |
| SCHEMBL13728481 | 0.76 | PDE10A (0.43) | PDE10ATRPA1PDGFRBPDGFRA | |
| SCHEMBL4886374 | 0.76 | PDE10A (0.44) | PDE10A | |
| SCHEMBL13686750 | 0.73 | MAOA (0.51) | TRPA1CYP19A1ALDH1A1PDGFRBPDGFRA | |
| SCHEMBL1705716 | 0.73 | MAOA (0.51) | TRPA1CYP19A1ALDH1A1PDGFRBPDGFRA | |
| SCHEMBL13830326 | 0.70 | P2RX3 (0.38) | PDE10ATRPA1FLT1ALDH1A1EGFR | |
| SCHEMBL30824358 | 0.70 | CYP11B1 (0.53) | PDE10AEGFR | |
| SCHEMBL15647524 | 0.70 | CYP11B1 (0.53) | PDE10AEGFR | |
| SCHEMBL2937347 | 0.70 | LMNA (0.46) | P2RX3P2RX2 | |
| SCHEMBL4729352 | 0.69 | IDO1 (0.42) | PDE10ACYP19A1ALDH1A1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2909205-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2015-08-26 | — | — | EP | disclosed |
| WO-2014062196-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-04-24 | — | — | WO | disclosed |
| EP-2721053-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2014-04-23 | — | — | EP | disclosed |
| EP-2705049-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2014-03-12 | — | — | EP | disclosed |
| WO-2012173983-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-12-20 | — | — | WO | disclosed |
| WO-2012151195-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-11-08 | — | — | WO | disclosed |