Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3716193 | 0.81 | ALDH1A1 (0.48) | LMNATDP1ALDH1A1KDM4ENNMT | |
| SCHEMBL20869196 | 0.79 | LMNA (0.42) | NPC1RAB9ASMN1; SMN2TP53TSHR | |
| SCHEMBL9190690 | 0.79 | LMNA (0.55) | LMNATDP1ALDH1A1KDM4ENNMT | |
| SCHEMBL13726677 | 0.78 | SIRT6 (0.55) | NPC1RAB9ASMN1; SMN2TP53TSHR | |
| SCHEMBL22256527 | 0.74 | GSK3B (0.40) | NPC1RAB9ASMN1; SMN2TP53TSHR | |
| SCHEMBL16319054 | 0.72 | NPC1 (0.38) | NPC1RAB9ASMN1; SMN2TP53TSHR | |
| SCHEMBL22256522 | 0.72 | LMNA (0.37) | NPC1RAB9ASMN1; SMN2TP53TSHR | |
| SCHEMBL22121995 | 0.72 | CYP2C19 (0.38) | NPC1RAB9ASMN1; SMN2TP53TSHR | |
| SCHEMBL30103450 | 0.72 | LMNA (0.38) | NPC1RAB9ASMN1; SMN2TP53TSHR | |
| SCHEMBL15508132 | 0.71 | LMNA (0.39) | NPC1RAB9ASMN1; SMN2TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151567-A1 | PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2012-11-08 | — | — | WO | disclosed |