Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | NNMT | P40261 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28553908 | 0.82 | CYP2C19 (0.37) | LMNATDP1CYP2C19NNMTKMO | |
| SCHEMBL24145048 | 0.82 | NNMT (0.39) | LMNATDP1CYP2C19NNMTKDM4E | |
| Hydrochloric Acid SCHEMBL22042737 | 0.81 | NNMT (0.38) | LMNATDP1CYP2C19NNMTKDM4E | |
| SCHEMBL9190690 | 0.80 | LMNA (0.55) | LMNATDP1NNMTKMOKDM4E | |
| SCHEMBL22121995 | 0.76 | CYP2C19 (0.38) | LMNATDP1CYP2C19NNMTKMO | |
| SCHEMBL20869196 | 0.76 | LMNA (0.42) | LMNATDP1CYP2C19NNMTKMO | |
| SCHEMBL1478401 | 0.75 | CYP2C19 (0.48) | LMNACYP2C19NNMTKDM4EALDH1A1 | |
| SCHEMBL20561605 | 0.74 | NNMT (0.39) | LMNATDP1CYP2C19NNMTKMO | |
| SCHEMBL13726677 | 0.74 | SIRT6 (0.55) | LMNATDP1CYP2C19NNMTKMO | |
| SCHEMBL3716193 | 0.74 | ALDH1A1 (0.48) | LMNATDP1CYP2C19NNMTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4097138-A1 | ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | Avila Therapeutics, Inc. (US) | 2022-12-07 | — | — | EP | disclosed |