Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13729789 | 0.88 | CYP19A1 (0.36) | NPC1RAB9A | |
| SCHEMBL2201862 | 0.78 | — | — | |
| SCHEMBL149516 | 0.77 | — | — | |
| SCHEMBL13726400 | 0.73 | CCR1 (0.52) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL3396456 | 0.72 | — | — | |
| SCHEMBL4859413 | 0.72 | — | — | |
| SCHEMBL13729734 | 0.72 | ALOX5 (0.39) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL13727304 | 0.72 | CCR1 (0.50) | — | |
| SCHEMBL6648783 | 0.67 | APLNR (0.34) | — | |
| SCHEMBL11058940 | 0.67 | HPGD (0.44) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151567-A1 | PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2012-11-08 | — | — | WO | disclosed |