⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13729792 | 0.72 | MEN1 (0.32) | — | |
| SCHEMBL149516 | 0.72 | — | — | |
| SCHEMBL2201862 | 0.68 | — | — | |
| SCHEMBL3396456 | 0.68 | — | — | |
| SCHEMBL13729789 | 0.64 | CYP19A1 (0.36) | — | |
| SCHEMBL11058940 | 0.64 | HPGD (0.44) | — | |
| SCHEMBL3170487 | 0.64 | MEN1 (0.43) | — | |
| SCHEMBL13727051 | 0.64 | LMNA (0.30) | — | |
| SCHEMBL6648783 | 0.64 | APLNR (0.34) | — | |
| SCHEMBL1684235 | 0.62 | LCK (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7390905-B2 | Piperidine compound and process for preparing the same | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-06-24 | — | — | US | disclosed |
| US-20070112029-A1 | Piperidine compound and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 2007-05-17 | — | — | US | disclosed |
| EP-1693367-A1 | PIPERIDINE COMPOUND AND METHOD FOR PRODUCING SAME | TANABE SEIYAKU CO., LTD. (JP) | 2006-08-23 | — | — | EP | disclosed |